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Tobacco
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Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke
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Willful or deliberate act of inhaling and exhaling SMOKE from burning substances or agents held by hand
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Tobacco used to the detriment of a person's health or social functioning. Tobacco dependence is included
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