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Title The computational mechanics of bone tissue : biological behaviour, remodelling algorithms and numerical applications / Jorge Belinha, Maria-Cristina Manzanares-Céspedes, António M.G. Completo, editors
Published Cham : Springer, 2020

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Description 1 online resource (249 pages)
Series Lecture Notes in Computational Vision and Biomechanics ; v. 35
Lecture notes in computational vision and biomechanics ; v. 35.
Contents Intro -- Preface -- Acknowledgements -- Contents -- Contributors -- Biological Characterization of Bone Tissue -- Bone: Functions, Structure and Physiology -- 1 Introduction -- 2 The Complexity Behind Simplicity -- 2.1 Bone Functions -- 2.2 Bone Structure and Mechanical Behaviour -- 2.3 Regulation of Bone Metabolism (Modelling/Remodelling) -- 2.4 Bone Remodelling and Cell Interchange -- 2.5 Bone Mechanotransduction -- 2.6 Mechanotransduction Mechanisms -- References -- Bone Quality Assessment at the Atomic Scale -- 1 Introduction -- 2 Hydroxyapatite -- 3 Rietveld Refinement Method
3.1 Crystallite Size and Microdeformations: Scherrer Equation and Williamson-Hall Graph -- 4 Ultrasonometry of the Calcaneus -- 5 Materials and Methods -- 5.1 Ethical Aspects -- 5.2 Materials -- 5.3 Samples Pre-selection -- 5.4 Sample Preparation and Characterization -- 5.5 DRX and Rietveld Method Parameters -- 6 Results and Discussion -- 6.1 Ultrasonometry Analysis -- 6.2 Scanning Electron Microscopy (SEM) -- 6.3 Dispersive Energy Spectroscopy (DES) -- 6.4 Microhardness (HK) -- 6.5 X-Ray Diffractometry (XRD) and the Rietveld Method -- 7 Conclusion -- References -- Bone Remodelling Algorithms
Meshless, Bone Remodelling and Bone Regeneration Modelling -- 1 Introduction -- 1.1 Bone Regeneration -- 1.2 Bone Remodelling -- 1.3 Meshless Methods -- 2 Bone Remodelling and Regeneration Modelling -- 2.1 Mechanoregulatory Models -- 2.2 Bioregulatory Models -- 2.3 Mechanobioregulatory Models -- 3 Meshless Methods Applications -- 3.1 Meshless Methods and Mechanics -- 3.2 Meshless Methods and Biomechanics -- 3.3 Meshless Methods and Bone Remodelling -- 4 Conclusion -- References
Dynamic Biochemical and Cellular Models of Bone Physiology: Integrating Remodeling Processes, Tumor Growth, and Therapy -- 1 Bone Remodeling Physiology -- 1.1 Healthy Bone Remodeling -- 1.2 Tumor in the Bone Remodeling Cycle -- 1.3 Bone Treatments -- 2 Mathematical Bone Remodeling Local Models -- 2.1 Healthy Remodeling Dynamics -- 2.2 Models Including Tumor Burden -- 2.3 Introducing Treatment -- 2.4 Models Based on Fractional and Variable Order Derivatives -- 3 Non-local Models -- 3.1 Healthy Bone Remodeling -- 3.2 Models Including the Tumor Burden -- 3.3 Non-local Treatment Approach
4 Conclusions and Future Work -- References -- Mathematical Modelling of Spatio-temporal Cell Dynamics Observed During Bone Remodelling -- 1 Introduction -- 2 Numerical Methods -- 2.1 Finite Element Method -- 2.2 Meshless Methods -- 3 New Spatio-temporal Model -- 3.1 Komarova's Model -- 3.2 Ayati's Model -- 3.3 Proposed Model -- 4 2D Bone Patch Analysis -- 4.1 Initial Conditions -- 4.2 Results and Discussion -- 5 Conclusion -- References -- A Mechanostatistical Approach to Multiscale Computational Bone Remodelling -- 1 Introduction -- 2 Part I: Macroscale FE Model -- 2.1 Model Construction
Summary This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field. -- Provided by publisher
Notes 2.2 Mechanical Simulations
Print version record
Subject Bones -- Mechanical properties.
Tissues -- Mechanical properties.
Bones -- Mechanical properties
Tissues -- Mechanical properties
Form Electronic book
Author Belinha, Jorge.
Manzanares-Céspedes, Maria-Cristina
Completo, António M. G
ISBN 9783030375416
3030375412
3030375404
9783030375409
9783030375423
3030375420
9783030375430
3030375439