| Description |
1 online resource |
| Contents |
Part 1. Epidemiology -- CQ1. What Are the Risk Factors for Thyroid Cancer? -- CQ2. Is There a Difference in Prognosis Between Adult Thyroid Cancer and Juvenile Thyroid Cancer or Juvenile Follicular Cancer? -- Column 1. Genetics of Thyroid Cancer -- Column 2. Prevalence of Various Histological Types of Thyroid Cancer -- Column 3. Anaplastic Transformation of Differentiated Carcinoma -- Column 4. Incidence, Morbidity, and Mortality of Thyroid Carcinoma in Japan |
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Part 2. Diagnosis and non-surgical management\n -- CQ3. What Is the Frequency (Probability of Cancer Before Examination) of Thyroid Cancer -- CQ4. What Are the Factors That Increase the Likelihood of Malignancy and What Is the Odds Ratio and Risk Ratio? -- CQ5. What Are the Physical Signs and Symptoms That Increase the Likelihood of Thyroid Cancer and What Are the Sensitivity and Specificity? -- CQ6. What Are the Imaging Studies Most Suitable for the Diagnosis of Thyroid Carcinoma and What Are Their Sensitivity, Specificity, and Likelihood Ratio? -- CQ7. What Are the Blood Chemistry Data That Increase the Likelihood of Thyroid Malignancy and What Are Their Sensitivity, Specificity, and Likelihood Ratio? -- CQ8. What Are the Sensitivity and Specificity of Aspiration Cytology? -- CQ9. What Are the Sensitivity and Specificity of Ultrasonography, CT, MRI, Laryngoscopy, and Bronchoscopy in the Preoperative Evaluation of Thyroid Cancer Invasion to the Trachea, Esophagus, and the Recurrent Laryngeal Nerve? -- CQ10. How Is the Natural History of Nodules Diagnosed as Benign (Growth and Reduction Rates)? -- CQ11. Does TSH Suppression Therapy Reduce the Size of Tumors Diagnosed as Benign? -- CQ12. What Is the Intra-Observer Variation in the Pathological Diagnosis of Follicular Carcinoma? -- CQ13. What Is the Efficacy of Percutaneous Ethanol Injection Therapy for Autonomously Functioning Thyroid Nodules? -- CQ14. Do Cystic Nodules Decrease in Volume by Aspiration and Drainage of Content Fluid and Percutaneous Ethanol Injection Therapy? -- CQ15. What Is the Likelihood That Multinodular Goiter Will Be Surgically Resected After Observation? -- Column 5. Indication for Surgery of Nodular Goiter -- Column 6. Diagnosis of Anaplastic Carcinoma |
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Part 3. Papillary carcinoma -- CQ16. What Is the Most Appropriate and Convenient Risk Classification System for Predicting the Prognosis of Patients with Papillary Carcinoma? -- CQ17. Does Total (or Near Total) Thyroidectomy Improve the Prognosis of Papillary Carcinoma Patients Compared to Lobectomy or Lobectomy Isthmectomy? -- CQ18. Does Central Compartment Dissection Improve the Prognosis of Papillary Carcinoma Patients? -- CQ19. Does Dissection of the Lateral Compartment Improve the Prognosis of Papillary Carcinoma Patients? -- CQ20. When Can Papillary Microcarcinoma (Papillary Carcinoma Measuring 1 cm or Less) Be Observed Without Immediate Surgery? -- Column 7. What Is the Acceptable Incidence for Persistent Recurrent Laryngeal Nerve Paralysis and Persistent Hypoparathyroidism as Complications of Thyroid Surgery? -- Column 8. The Controversy Regarding the Extent of Thyroidectomy for Papillary Carcinoma and Actual Practice in Japan -- Column 9. Lobectomy and Paratracheal Node Dissection |
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Part 4. Follicular tumor -- Introduction -- CQ21. Is It Possible to Diagnose Follicular Carcinoma on Preoperative FNA or Intraoperative Frozen Section Diagnosis? -- CQ22. Does Classification of Follicular Carcinoma According to the Degree of Invasiveness (Widely Invasive and Minimally Invasive Types) Reflect the Prognosis? -- CQ23. When Is Completion Total Thyroidectomy Recommended as a Second Surgery for Patients Who Underwent Hemithyroidectomy and Were Diagnosed as Having Follicular Carcinoma on Postoperative Pathological Examination? -- CQ24. Does Total Thyroidectomy with Radioactive Iodine Ablation and TSH Suppression Therapy Improve Patient Prognosis with Widely Invasive Follicular Carcinoma Compared to Only Limited Thyroidectomy? -- CQ25. Does Prognosis of Oxyphilic (Hurthle Cell) Follicular Carcinoma Differ from That of Conventional Follicular Carcinoma? |
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Part 5. Medullary carcinoma -- CQ26. What Is the Usefulness of RET Gene Mutation Analysis for Medullary Carcinoma? -- CQ27. What Are the Incidences of Diseases Associated with Hereditary Medullary Carcinoma? -- CQ28. Do Total Thyroidectomy and Lymph Node Dissection for Sporadic and Hereditary Medullary Carcinoma Improve the Prognosis? -- CQ29. Is Chemotherapy Effective for Advanced or Relapsed Medullary Carcinoma? -- CQ30. What Are Prognostic Factors of Medullary Carcinoma? |
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Part 6. Poorly differentiated carcinoma -- CQ31. What Is the Definition of Poorly Differentiated Carcinoma? What Is Its Prevalence and Prognosis? -- CQ32. Can Poorly Differentiated Carcinoma Be Diagnosed Preoperatively? -- CQ33. Do Total Thyroidectomy and Prophylactic Lymph Node Dissection Improve the Prognosis of Patients with Poorly Differentiated Carcinoma? -- CQ34. Does Additional Surgery Improve the Prognosis of Patients Who Underwent Hemithyroidectomy Under a Diagnosis of Papillary or Follicular Carcinoma, But Who Are Later Diagnosed as Having Poorly Differentiated Carcinoma on Postoperative Pathological Examination? -- CQ35. Do Therapies Other Than Surgery Improve the Prognosis for Patients with Poorly Differentiated Carcinoma? -- Column 10. Carcinoma Showing Thymus-Like Differentiation/Intrathyroidal Epithelial Thymoma |
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Part 7. Anaplastic carcinoma -- Introduction -- CQ36. Does Surgical Treatment for Anaplastic Carcinoma Improve Prognosis? -- CQ37. Do Adjuvant Therapies Improve the Prognosis of Anaplastic Carcinoma in Patients Who Underwent Curative Surgery? -- CQ38. Does Combined Modality Therapy for Anaplastic Carcinoma Improve Prognosis? -- CQ39. Should Relapsed Lesions of Differentiated Carcinoma That Were Diagnosed as Anaplastic Carcinoma Be Treated as Anaplastic Carcinoma? -- Column 11. When Should Palliative Care Be Considered? Is the Prognosis Explained to Patients? -- Column 12. Squamous Cell Carcinoma of the Thyroid Is Currently Classified as a Different Histology from Anaplastic Carcinoma. Are Therapeutic Strategies and Prognosis of Squamous Cell Carcinoma Similar to Those of Anaplastic Carcinoma? |
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Part 8. Radiation therapy -- CQ40. What Are Applications and Roles of Ablation? -- CQ41. Is Iodine Restriction Necessary Before Ablation? -- CQ42. What Is the Appropriate Dose of 131I? -- CQ43. What Is the Benefit of RAI Therapy for Local Recurrence, Lymph Node Metastasis and Distant Metastasis of Differentiated Thyroid Carcinoma? -- CQ44. What Is the Application, Effect and Safety of Recombinant Human Thyroid Stimulating Hormone (rhTSH)? -- Column 13. Comments on RAI Therapy Including the Actual Situation in Japan -- Column 14. Applications for External Beam Radiotherapy for Differentiated Thyroid Carcinoma -- Column 15. Is it Appropriate to 131I Scintigraphy Before RAI Therapy? What Is the Dose? -- Column 16. What Is the Actual Status of Radiotherapy (External Beam Radiotherapy and 131I MIBG Therapy)? -- Column 17. What Are the Side Effects of RAI Therapy and What Is Their Frequency? |
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Part 9. Surgical Treatment for Advanced Differentiated Carcinoma -- CQ45. What Is the Indication for Resection of the Recurrent Laryngeal Nerve for Cases Extending There? -- CQ46. Is Phonetic Function Improved by Reconstruction of the Recurrent Laryngeal Nerve? -- CQ47. For Cases Extending to the Trachea, Does Sleeve Resection of the Trachea Improve the Survival Rate Compared to Partial Resection (Wedge Resection or Window Resection)? -- CQ48. Does Tracheal Resection Improve the Survival Rate Compared with No Resection? -- Column 18. Treatment and Management Approaches for Cases Extending to the Trachea with Larynx, Esophagus, or Mediastinum Involvement |
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Part 10. Postoperative observation of differentiated carcinoma and treatment for inoperable cases -- CQ49. Does TSH Suppression Therapy After Surgery for Differentiated Thyroid Carcinoma Improve Survival? -- CQ50. Is Serum Thyroglobulin Measurement Useful as a Marker of Carcinoma Recurrence After Surgery? -- CQ51. Are Measurements of Calcitonin and CEA Useful as Markers of Recurrence After Surgery for Medullary Carcinoma? -- CQ52. What Are Useful Imaging Studies to Detect Lesions of Recurrence for Medullary Carcinoma with Elevation of Postoperative Calcitonin Level? -- CQ53. Is Chemotherapy for Advanced Thyroid Carcinoma Effective? -- CQ54. Is Percutaneous Ethanol Injection Therapy Effective for Local or Lymph Node Recurrence and Bone Metastasis? -- CQ55. Are Alternate Therapies Effective for Thyroid Carcinoma? -- Column 19. How Long Should Patients with Differentiated Thyroid Carcinoma Be Followed After Surgery? |
| Summary |
Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future |
| Analysis |
Medicine |
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Endocrinology |
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Oncology |
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Surgery |
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Medicine & Public Health |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Thyroid gland -- Cancer -- Treatment -- Japan
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Thyroid Neoplasms
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Thyroid Neoplasms -- therapy
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Thyroid Neoplasms -- surgery
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HEALTH & FITNESS -- Diseases -- Cancer.
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MEDICAL -- Oncology.
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Médecine.
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Thyroid gland -- Cancer -- Treatment
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| SUBJECT |
Japan |
| Subject |
Japan
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| Form |
Electronic book
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| Author |
Takami, Hiroshi.
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Ito, Yasuhiro, Dr.
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| ISBN |
9784431540496 |
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4431540490 |
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4431540482 |
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9784431540489 |
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