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E-book

Title Thyroid gland development and function / volume editors, Guy Van Vliet, Michel Polak
Published Basel ; New York : Karger, ©2007

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Description 1 online resource (x, 192 pages) : illustrations (some color)
Series Endocrine development, 1421-7082 ; v. 10
Endocrine development ; v. 10. 1421-7082
Contents Murine models for the study of thyroid gland development / M. De Felice, R. Di Lauro -- Familial forms of thyroid dysgenesis / M. Castanet, M. Polak, J. Léger -- Possible non-Mendelian mechanisms of thyroid dysgenesis / J. Deladoëy, G. Vassart, G. Van Vliet -- Thyroid imaging in children / C. Garel, J. Léger -- Clinical and biological consequences of iodine deficiency during pregnancy / D. Glinoer -- Ontogenesis of thyroid function and interactions with maternal function / M.J. Obregon [and others] -- New phenotypes in thyroid dyshormonogenesis: hypothyroidism due to DUOX2 mutations / J.C. Moreno, T.J. Visser -- Thyroid hormone transporter defects / A. Grüters -- Novel biological and clinical aspects of thyroid hormone metabolism / A.M. Dumitrescu, S. Refetoff -- Papillary and follicular thyroid cancers in children / V. Vasko [and others] -- Hereditary medullary thyroid carcinoma: how molecular genetics made multiple endocrine neoplasia type 2 a paediatric disease / G. Szinnai, S. Sarnacki, M. Polak
Summary As is the case in all fields of medicine, developmental endocrinology is now being studied at the molecular level. In this volume world-class researchers review the advances of the past decade in the study of normal and abnormal organogenesis of the thyroid gland and of the ontogeny of its function. They describe human thyroid development and its defects with the help of genetic studies in mouse models. Genetic defects of thyroid hormone synthesis are covered and their clinical relevance debated. The important field of thyroid cancer in the context of spontaneous occurrence and as part of familial neoplasia syndromes is described in detail. Finally, the important problem of environmental iodine deficiency which has emerged as a global public health concern is addressed. For the first time, a decade of work is presented in a concise and highly readable form. Offering valuable insight both for senior clinicians and graduate students, this publication will be of central interest to basic scientists involved in developmental biology as well as to pediatricians and endocrinologists dealing with patients with congenital disorders of thyroid function
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Thyroid gland -- Diseases.
Thyroid gland -- Pathophysiology
Thyroid gland -- Growth
Thyroid Gland -- growth & development
Thyroid Gland -- physiology
Thyroid Gland -- physiopathology
Thyroid Diseases
Thyroid Diseases -- genetics
Thyroid gland -- Diseases
Schilddrüsenkrankheit -- Aufsatzsammlung.
Form Electronic book
Author Van Vliet, Guy
Polak, Michel
ISBN 9783805580755
3805580754
380558296X
9783805582964