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Title Signaling Mechanisms Regulating T Cell Diversity and Function / Jonathan Soboloff, Dietmar J. Kappes
Published CRC Press, 2017


Description 1 online resource (274 pages : 25 illustrations
Series Methods in Signal Transduction Series
Methods in signal transduction.
Contents Consequences of blocking the choreography of double negative thymocyte maturation / John Barnet -- In situ analysis of T cell receptor signals during positive selection / Nathalie Labrecque, Mengqi Dong, Aditi Sood, and Heather J. Melichar -- Regulation of negative selection in the thymus by cytokines : novel role of IL-23 to regulate ROR[gamma]t / John D. Mountz, Robert Lowe, Hao Li, and Hui-Chen Hsu -- Modulating thymic negative selection with bioengineered thymus organoids / Massimo Trucco, Isha Pradhan, Asako Tajima, Suzanne Bertera, and Yong Fan -- Characterizing the role of ThPok in cd4/cd8 selection / Dietmar Kappes -- TCR signaling circuits in a[beta]/d[gamma] T lineage choice / David Wiest, Shawn P. Fahl, and Dietmar J. Kappes -- Phenotypic and functional characterization of regulatory T cell populations / Talal Chatila and Louis-Marie Charbonnier -- T cell factor 1, mTOR and NKT development / Jyoti Sen, Nicola M. Heller, Rosa Berga-Bolanos, and Lynette Naler -- Transmission of T cell receptor-mediated signaling via the GRB2 family of adaptor proteins / Jon C.D. Houtman and Mahmood Y. Bilal -- Defining the roles of Ca2+ signals during T cell activation / Elsie Samakai, Christina Go, and Jonathan Soboloff -- Histone methyltransferases and T cell heterogeneity / Janaki Purushe and Yi Zhang -- Models of regulatory T cell alterations and systemic autoimmunity / Jonathan Cho, Dorina Avram, and Kyle J. Lorentsen
Bibliography Includes bibliographical references at the end of each chapters and index
Notes Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL
Subject T cells.
Cellular signal transduction.
Receptors, Antigen, T-Cell -- immunology
TCF Transcription Factors
T-Lymphocytes -- immunology
Signal Transduction
Thymus Gland -- metabolism
SCIENCE -- Life Sciences -- Cytology.
SCIENCE -- Life Sciences -- Biology -- Molecular Biology.
Cellular signal transduction.
T cells.
Form Electronic book
Author Soboloff, Jonathan, editor
Kappes, Dietmar J., editor
ISBN 9781498705097