| Description |
1 online resource (xxiii, 1095 pages) : illustrations (some color) |
| Series |
Advances in experimental medicine and biology ; v. 704 |
|
Advances in experimental medicine and biology ; v. 704. 0065-2598
|
| Contents |
Structural biology of TRP channels / Minghui Li, Yong Yu, and Jian Yang -- Functional and structural studies of TRP channels heterologously expressed in budding yeast / Vera Moiseenkova-Bell and Theodore G. Wensel -- Natural product ligands of TRP channels / Irina Vetter and Richard J. Lewis -- Synthetic modulators of TRP channel activity / Christian Harteneck, Chihab Klose, and Dietmar Krautwurst -- Study of TRP channels by automated patch clamp systems / Morten Sunesen and Rasmus B. Jacobsen -- TRPC2: of mice but not men / Christoffer Löf [and others] -- TRPM1: New trends for an old TRP / Elena Oancea and Nadine L. Wicks -- The non-selective monovalent cationic channels TRPM4 and TRPM5 / Romain Guinamard, Laurent Sallé, and Christophe Simard -- TRPM7, the Mg2+ inhibited channel and kinase / Chris Bates-Withers, Rajan Sah, and David E. Clapham -- TRPM8 in health and disease: cold sensing and beyond / Yi Liu and Ning Qin -- TRPML1 / Grace A. Colletti and Kirill Kiselyov -- TRPML2 and the evolution of mucolipins / Emma N. Flores and Jaime García-Añoveros -- The TRPML3 channel: from gene to function / Konrad Noben-Trauth -- TRPV5 and TRPV6 in transcellular Ca2+ transport: regulation, gene duplication, and polymorphisms in African populations / Ji-Bin Peng -- The TRPV5 promoter as a tool for generation of transgenic mouse models / Marlene Vind Hofmeister [and others] -- TRPP channels and polycystins / Alexis Hofherr and Michael Köttgen -- TRP channels in yeast / Marta Kaleta and Christopher Palmer -- C. elegans TRP channel / Rui Xiao and X.Z. Shawn Xu -- Investigations of TRP channel function in vivo using frog and zebrafish model systems / Robert A. Cornell -- TRP channels in parasites / Adrian J. Wolstenholm, Sally M. Williamson, and Barbara J. Reaves -- Receptor signaling integration by TRP channelsomes / Yasuo Mori [and others] -- Gating mechanisms of canonical transient receptor potential channel proteins:role of phosphoinositols and diacylglycerol / Anthony P. Albert -- The TRPC ion channels: association with Orai1 and STIM1 proteins and participation in capacitative and non-capacitative calcium entry / Gines M. Salido, Isaac Jardín, and Juan A. Rosado -- Contribution of TRPC1 and Orai1 to Ca2+ entry activated by store depletion / Kwong Tai Cheng [and others] -- Primary thermosensory events in cells / Ilya Digel -- ThermoTRP channels: biophysics of polymodal receptors / David Baez-Nieto [and others] -- Complex regulation of TRPV1 and related thermoTRPs: implications for therapeutic intervention / Rosa Planells-Cases [and others] -- Voltage sensing in thermo TRP channels / Sebastian Brauchi and Patricio Orio -- TRP channels as mediators of oxidative stress / Barbara A. Miller and Wenyi Zhang -- Regulation of TRP signaling by ion channel translocation between cell compartments / Alexander C. Cerny and Armin Huber -- Emerging roles of canonical TRP channels in neuronal function / Sunitha Bollimuntha, Senthil Selvaraj, and Brij B. Singh -- TRP channels and neural persistent activity / Antonio Reboreda, Lydia Jiménez-Díaz, and Juan D. Navarro-López -- Role of TRP channels in pain sensation / Man-Kyo Chung, Sung Jun Jung, and Seog Bae Oh -- TRPV1: a therapy target that attracts the pharmaceutical interests / Rong Xia [and others] -- Expression and function of TRP channels in liver cells / Grigori Y. Rychkov and Gregory J. Barritt -- Expression and physiologial roles of TRP channels in smooth muscle cells / Christelle Guibert, Thomas Ducret, and Jean-Pierre Savineau -- TRPM channels in the vasculature / Alexander Zholos [and others] -- Molecular expression and functional role of canonical transient receptor potential channels in airway smooth muscle cells / Yong-Xiao Wang and Yun-Min Zheng -- TRP channels in skeletal muscle: gene expression, function and implication for disease / Heinrich Brinkmeier -- TRP Channels in vascular endothelial cells / Ching-On Wong and Xiaoqiang Yao -- TRP channels in the cardiopulmonary vasculature / Alexander Dietrich and Thomas Gudermann -- TRP channels of islets / Md. Shahidul Islam -- Multiple roles for TRPs in the taste system: not your typical TRPs / Kathryn F. Medler -- Roles of transient receptor potential proteins (TRPs) in epidermal keratinocytes / Mitsuhiro Denda and Moe Tsutsumi -- TRP channels in urinary bladder mechanosensation / Isao Araki -- The role of TRP ion channels in testicular function / Pradeep G. Kumar and Mohammed Shoeb -- TRP channels in female reproductive organs and placenta / Janka Dörr and Claudia Fecher-Trost -- Oncogenic TRP channels / Vʹyacheslav Lehenʹkyi and Natalia Prevarskaya -- TRPV channels in tumor growth and progression / Giorgio Santoni, Valerio Farfariello, and Consuelo Amantini -- The role of transient receptor potential channels in respiratory symptoms and athophysiology / M. Allen McAlexander and Thomas Taylor-Clark -- TRP channels and psychiatric disorders / Loris A. Chahl -- Transient receptor potential genes and human inherited disease / Kate V. Everett |
| Summary |
Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves |
| Analysis |
fysiologie |
|
physiology |
|
biomedische wetenschappen |
|
biomedicine |
|
levenswetenschappen |
|
life sciences |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
TRP channels.
|
|
Transient Receptor Potential Channels
|
|
SCIENCE -- Life Sciences -- Biochemistry.
|
|
TRP channels
|
| Form |
Electronic book
|
| Author |
Islam, Md. Shahidul, 1956-
|
| ISBN |
9789400702653 |
|
9400702655 |
|
