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Author Wodarz, Dominik.

Title Killer cell dynamics : mathematical and computational approaches to immunology / Dominik Wodarz
Published New York : Springer, 2007
Online access available from:
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Description 1 online resource (xiii, 220 pages) : illustrations
Series Interdisciplinary applied mathematics ; v. 32
Interdisciplinary applied mathematics ; v. 32
Contents Front Matter; Viruses and Immune Responses: A Dynamical View; Models of CTL Responses and Correlates of Virus Control; CTL Memory; CD4 T Cell Help; Immunodominance; Multiple Infections and CTL Dynamics; Control versus CTL-Induced Pathology; Lytic versus Nonlytic Activity; Dynamical Interactions between CTL and Antibody Responses; Effector Molecules and CTL Homeostasis; Virus-Induced Subversion of CTL Responses; Boosting Immunity against Immunosuppressive Infections; Evolutionary Aspects of Immunity; Back Matter
Summary "This book reviews how mathematics can be used in combination with biological data in order to improve understanding of how the immune system works. This is illustrated largely in the context of viral infections. Mathematical models allow scientists to capture complex biological interactions in a clear mathematical language and to follow them to their precise logical conclusions. This can give rise to counter-intuitive insights which would not be attained by experiments alone, and can be used for the design of further experiments in order to address the mathematical results."--Jacket
Bibliography Includes bibliographical references (pages 195-216) and index
Notes Print version record
In Springer e-books
Subject Killer cells.
T cells.
Virus diseases -- Immunological aspects.
Immune response -- Mathematical models.
T-Lymphocytes, Cytotoxic -- immunology.
Computational Biology -- methods.
Immunity, Cellular.
Models, Immunological.
Form Electronic book
LC no. 2006931001
ISBN 0387308938 (Cloth)
9780387308937 (Cloth)