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Title Superantigens : molecular basis for their role in human diseases / edited by Malak Kotb and John D. Fraser
Published Washington, D.C. : ASM Press, ©2007

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Description 1 online resource (xii, 263 pages) : illustrations (some color)
Series Monograph, ASM Press
Monograph, ASM Press
Contents The streptococcal superantigens / John D. Fraser and Thomas Proft -- Staphylococcal and streptococcal superantigens : an update / Patrick M. Schlievert and Gregory A. Bohach -- Mycoplasma arthritidis-derived superantigen (MAM), a unique class of superantigen that bridges innate and adaptive immunity / Barry C. Cole and Hong-Hua Mu -- Viral superantigens in mice and humans / Albert K. Tai and Brigitte T. Huber -- Superantigens from gram-negative bacteria and the diseases that they cause / Takehiko Uchiyama, Tohru Miyoshi-Akiyama, and Hidehiro Ueshiba -- Superantigen architecture : functional decoration on a conserved scaffold / Vickery L. Arcus and Edward N. Baker -- Structural evidence for zinc and peptide dependence in superantigen major histocompatibility complex class II interaction / Björn Walse -- Superantigens : structure, function, and diversity / Matthew D. Baker and K. Ravi Acharya
Role of superantigens in skin disease / Sang-Hyun Cho and Donald Y.M. Leung -- Pathogenetic mechanisms and therapeutic approaches in superantigen-induced experimental autoimmune diseases / Andrej Tarkowski -- Experimental models of superantigen-mediated neuropathology / Malte E. Kornhuber [and others] -- Novel experimental models for dissecting genetic susceptibility of superantigen-mediated diseases / Eva Medina -- Intravenous immunoglobulin therapy in superantigen-mediated toxic shock syndrome / Anna Norrby-Teglund, Donald E. Low, and Malak Kotb -- Broad-spectrum peptide antagonists of superantigen toxins / Revital Levy [and others] -- Small nonpeptide inhibitors of staphylococcal superantigen-induced cytokine production and toxic shock / Teresa Krakauer -- Countermeasures against superantigens : structure-based design of bispecific receptor mimics / Goutam Gupta and Meghan Kunkel
Summary A team of internationally respected researchers covers the basic molecular mechanisms of superantigen action, their structure and function, and their role in human diseases
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Superantigens.
Superantigens -- physiology
Superantigens
Bacteria -- immunology
Virulence Factors
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Superantigens
Form Electronic book
Author Kotb, Malak, editor.
Fraser, John D., editor.
ISBN 9781555815844
1555815847
1283034131
9781283034135
9786613034137
6613034134