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Title Behavioral and biochemical issues in substance abuse / Frank R. George, Doris Clouet, guest editors ; Barry Stimmel, editor
Published New York : Haworth Press, [1991]
©1991

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Description 1 online resource (249 pages) : illustrations
Contents Editorial : Behavioral and biochemical genetic issues in substance abuse / Frank R. George, Doris Clouet -- Genetic selections for nicotine and cocaine sensitivity in mice / Andrew Smolen, Michael J. Marks -- Where are the mu receptors that mediate opioid analgesia? An autoradiographic study in the HAR and LAR selection lines / J.K. Belknap [and others] -- Behavioral and neurochemical studies in diazepam-sensitive and resistant mice / Edward J. Gallaher, Susanne E. Gionet, Daniel J. Feller -- Animal models for the study of alcoholism : utility of selected lines / J.C. Froehlich, T.K. Li -- Use of recombinant inbred strains to assess vulnerability to drug abuse at the genetic level / Tamara J. Phillips, John K. Belknap, John C. Crabbe -- The use of recombinant inbred strains to study mechanisms of drug action / Jeanne M. Wehner, June I. Pounder, Barbara J. Bowers -- Progress towards the development of animal models of smoking-related behaviors / Allan C. Collins, Michael J. Marks -- Is there a common biological basis for reinforcement from alcohol and other drugs? / Frank R. George -- Genetic determinants of susceptibility to the rewarding and other behavioral actions of cocaine / Thomas W. Seale, John M. Carney -- Issues surrounding the assessment of the genetic determinants of drugs as reinforcing stimuli / John M. Carney [and others] -- Establishment of drug discrimination and drug reinforcement in different animal strains : some methodological issues / Richard A. Meisch -- Biochemical genetic differences in vulnerability to drug effects : is statistically significant always physiologically important and vice versa? / Mary C. Ritz -- Genetic influence in human substance abuse / Roy W. Pickens, Dace S. Svikis -- Methodological issues in genetic studies of human substance abuse / Dace S. Svikis, Roy W. Pickens -- The use of nonneuronal cells as an In Vitro model ssytem for studying the genetic component of cellular response to opiates and other drugs of abuse / John J. Madden, Arthur Falek -- Behavioral and biochemical issues in substance abuse / Lynn Kasner Morgan, James E. Raper, Jr
Summary This excellent book is a concise yet thorough examination of the important and emerging field of the study of biological risk factors in drug abuse. Historically, drug abuse research has concentrated on the contributions of environmental and behavioral factors as the major influences on addiction. The revelatory studies in this volume examine the genetic contributions to drug taking behavior through the use of animal models, cellular experiments and human clinical studies. Behavioral and Biochemical Issues in Substance Abuse provides for the first time in one volume, up-to-date, easily digeste
Notes "Has also been published as Journal of addictive diseases, volume 10, numbers 1/2, 1991"--Title page verso
Bibliography Includes bibliographical references
Notes Print version record
Subject Substance abuse -- Genetic aspects -- Congresses
Neuropsychopharmacology -- Congresses
Neuropharmacology.
Psychopharmacology.
Substance-Related Disorders -- genetics
Neuropharmacology
Psychopharmacology
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Psychopharmacology
Neuropharmacology
Neuropsychopharmacology
Substance abuse -- Genetic aspects
Drogenabhängigkeit
Erblichkeit
Aufsatzsammlung
Rauschgift
Sucht
Verhalten
Tierversuch
Genre/Form Festschriften
Conference papers and proceedings
Festschriften.
Form Electronic book
Author George, Frank Richard
Clouet, Doris H
Stimmel, Barry, 1939-
ISBN 9781317837770
1317837770