| Description |
1 online resource (xxv, 531 pages) : illustrations |
| Contents |
pt. 1. Overview -- pt. 2. Biosynthesis, transport of sphingolipids -- pt. 3. Generation and degradation of sphingolipid signaling molecules -- pt. 4. Membrane domain and biological function -- pt. 5. Membrane lipid domain and human pathobiology -- pt. 6. S1P signaling and SIPR -- pt. 7. Advanced technology in sphingolipid biology |
| Summary |
Sphingolipids are fundamental to the structures of cell membranes, lipoproteins, and the stratum cornea of the skin. Many complex sphingolipids as well as simpler sphingoid bases and derivatives are highly bioactive as extra- and intracellular regulators of growth, differentiation, migration, survival, senescence, and numerous cellular responses to stress. This book provides many examples of exciting new developments in sphingolipid biology/sphingolipidology that are changing our understanding of how multicellular organisms grow, develop, function, age, and die. The key areas addressed include sphingolipid biosynthesis, transport and membrane organization/lipid rafts; genetic approaches to understanding the roles of membrane sphingolipid biosynthesis; sphingolipid metabolism, specific G protein-coupled receptors (GPCRs), and signal transduction; and sphingolipid-associated disease and drug development |
| Analysis |
biochemie |
|
biochemistry |
|
celbiologie |
|
cellular biology |
|
sphingolipiden |
|
sphingolipids |
|
lipiden |
|
lipids |
|
Cellular Biology |
|
Celbiologie |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Sphingolipids.
|
|
Cell interaction.
|
|
Sphingolipids -- physiology
|
|
Cell Communication
|
|
Sphingolipids
|
|
SCIENCE -- Life Sciences -- Cell Biology.
|
|
Sphingolipids -- physiology.
|
|
Cell Communication.
|
|
Sphingolipids.
|
|
Biomédecine.
|
|
Sciences de la vie.
|
|
Cell interaction
|
|
Sphingolipids
|
| Form |
Electronic book
|
| Author |
Hirabayashi, Y. (Yoshio)
|
|
Igarashi, Y. (Yasuyuki)
|
|
Merrill, Alfred H. (Alfred Harrison), 1951-
|
| ISBN |
9784431342007 |
|
4431342001 |
|
4431341986 |
|
9784431341987 |
|
1281216836 |
|
9781281216830 |
|
