| Description |
1 online resource |
| Contents |
Preface; References; Contents; 1: Historical Background and Glossary of the Apnea Phenomenon; 1.1 Introduction; 1.2 From Hippocrates to Hunter, Cheyne and Stokes: Watching the Ill Breathing; 1.3 Between Nineteenth and Twentieth Century: The Golden Age of Physiology; 1.4 From the Birth of Sleep Medicine to the Rediscovery of PB/CSR in Heart Failure; 1.5 Appendix: A Brief Dictionary of Breathlessness; References; 2: Mechanics and Chemistry of Respiration in Health; 2.1 Introduction; 2.2 Functional Pulmonary Anatomy and Mechanics of Ventilation; 2.2.1 Functional Pulmonary Anatomy |
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2.2.1.1 Pulmonary Volumes2.2.1.2 Respiratory Muscles; 2.2.1.3 Pulmonary Circulation; 2.2.2 The Mechanical Substrate of Respiration; 2.2.2.1 Resistances; Elastic Resistances; Non-elastic Resistances; Turbulent Flux Resistances; 2.2.2.2 Pulmonary, Thoracic and Thoracopulmonary Compliances; 2.2.2.3 The Intrapleural Pressure; 2.3 Pulmonary Gas Exchange; 2.3.1 Alveolar Structure, Surfactant and Alveolar Gas Exchange; 2.3.2 The Ventilation to Perfusion Ratio in Physiological and Pathological Conditions; 2.3.3 Modulation of Gas Transport by Haemoglobin; 2.3.3.1 CO2 Transportation |
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2.4 Central Control of Ventilation2.5 Functional Architecture of Chemoreceptive Control of Ventilation; 2.5.1 Peripheral Chemoreceptors; 2.5.2 Central Chemoreceptors; 2.5.3 Key Features of Chemoreflexes; 2.5.3.1 Hypoxic Ventilatory Response (Fig. 2.3); 2.5.3.2 Hypercapnic Ventilatory Response (Fig. 2.4); 2.5.3.3 Integration of Central and Peripheral Chemoreflexes; References; 3: Hypopneas and Apneas as Physiological and Pathological Phenomena Throughout the Life Span; 3.1 Introduction; 3.2 Pediatric Apneas and Sudden Infant Death Syndrome; 3.2.1 Definition; 3.2.2 Epidemiology |
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3.2.3 Clinical Presentation, Risk Factors, and Complications3.2.4 Pathophysiology; 3.2.5 Treatment; 3.3 Diverse Central Apneas in Physiological and Pathological Conditions; 3.3.1 Idiopathic Central Sleep Apnea; 3.3.1.1 Definition; 3.3.1.2 Epidemiology and Clinical Presentation; 3.3.1.3 Pathophysiology; 3.3.1.4 Treatment; 3.3.2 Apneas at High Altitude; 3.3.2.1 Definition; 3.3.2.2 Clinical Presentation; 3.3.2.3 Pathophysiology; 3.3.2.4 Treatment; 3.3.3 Periodic Breathing in Neurological Diseases; 3.3.3.1 Definition; 3.3.3.2 Epidemiology and Clinical Presentation |
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3.3.3.3 Pathophysiology3.3.3.4 Treatment; 3.3.4 Periodic Breathing and Kidney Failure; 3.3.4.1 Definition; 3.3.4.2 Epidemiology; 3.3.4.3 Clinical Implications and Complications; 3.3.4.4 Pathophysiology; 3.3.4.5 Treatment; 3.3.5 Periodic Breathing and Pulmonary Hypertension; 3.3.5.1 Definition; 3.3.5.2 Epidemiology and Risk Factors; 3.3.5.3 Clinical Implications and Complications; 3.3.5.4 Pathophysiology; 3.3.5.5 Treatment; 3.4 Obstructive Sleep Apnea; 3.4.1 Definition; 3.4.2 Epidemiology and Risk Factors; 3.4.3 Clinical Implications and Complications; 3.4.4 Pathophysiology |
| Summary |
This book systematically focuses on central sleep apneas, analyzing their relationship especially with heart failure and discussing recent research results and emerging treatment strategies based on feedback modulation. The opening chapters present historical background information on Cheyne-Stokes respiration (CSR), clarify terminology, and explain the mechanics and chemistry of respiration. Following a description of the physiology of respiration, the pathophysiology underlying central apneas in different disorders and particularly in heart failure is discussed. The similarities and differences of obstructive and central apneas are then considered. The book looks beyond the concept of sleep apnea to daytime CSR and periodic breathing during effort and contrasts the opposing views of CSR as a compensatory phenomenon or as detrimental to the failing heart. The diagnostic tools currently in use for the detection of CSR are thoroughly reviewed, with guidance on interpretation of findings. The book concludes by describing the various forms of treatment that are available for CSR and by explaining how to select patients for treatment |
| Bibliography |
Includes bibliographical references |
| Subject |
Apnea.
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Heart failure.
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Comorbidity.
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Polysomnography.
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Cheyne-Stokes Respiration -- physiopathology
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Heart Failure -- physiopathology
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Comorbidity
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Polysomnography
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Sleep Apnea Syndromes -- physiopathology
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Apnea
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Heart Failure
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Multimorbidity
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Polysomnography
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Comorbidity
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Apnea
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Heart failure
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| Form |
Electronic book
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| Author |
Emdin, Michele, editor.
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Giannoni, Alberto, editor
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Passino, Claudio, editor
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| ISBN |
9783319263540 |
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3319263544 |
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