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Book Cover
E-book
Author Sambhara, Suryaprakash

Title Nucleic acid sensors and antiviral immunity / Suryaprakash Sambhara, Takashi Fujita
Published Austin, Tex. : Landes Bioscience, ©2013

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Description 1 online resource
Series Molecular biology intelligence unit
Molecular biology intelligence unit.
Contents COVER; TITLE PAGE. Nucleic Acid Sensors and Antiviral Immunity; Copyright ©2013 Landes Bioscience; DEDICATION; About the Editors ... Suryaprakash Sambhara; About the Editors ... Takashi Fujita; CONTENTS; EDITORS AND CONTRIBUTORS; FOREWORD by Luke A.J. O'Neill; PREFACE; Chapter 1. Antiviral Responses in Invertebrates; Chapter 2. Overview of TLRs; Chapter 3. Nucleic Acid-Sensing TLR Signaling Pathways; Chapter 4. Alternative Regulatory Mechanisms of TLR Signaling; Chapter 5. Intracellular Viral RNA Sensors: RIG-I Like Receptors; Chapter 6. Contribution of LGP2 to Viral Recognition Pathways
Chapter 7. The Mitochondrial Immune Signaling ComplexChapter 8. DNA Sensors and Anti-Viral Immune Responses; Chapter 9. Mechanisms of Interferon Antagonism by Poxviruses; Chapter 10. Innate Immune Evasion Strategies of HCV and HIV: Common Themes for Chronic Viral Infection; Chapter 11. Innate Immune Evasion Strategies of Influenza A Virus; Chapter 12. Autophagy in Antiviral Immunity; Chapter 13. Synthetic and Natural Ligands of RLR; Chapter 14. Antiviral Actions of Double-Stranded RNA; Chapter 15. Ligands of Pathogen Sensors as Antiviral Agents; INDEX; Symbols-D; E-I; J-P; R-T; U-V
Summary Nucleic Acid Sensors and Antiviral Immunity presents a timely and extensive account of the detection of nucleic acids in infection and inflammation. This book represents an unprecedented account of this important aspect of immunology, by a stellar cast of authors who have defined the field. We have a key resource which should act as a primary source of information. The chapters will inspire researchers to continue on their quest to provide mechanistic insights into anti-viral innate immunity. The discoveries provide us with new strategies in the never ending war between humanity and viral infe
Bibliography Includes bibliographical references and index
Notes Online resource; title from digital title page (viewed on May 6, 2013)
Subject Immunology.
Natural immunity.
Nucleic Acids -- metabolism
Antigens, Viral -- immunology
Immunity, Innate
Signal Transduction -- immunology
Toll-Like Receptors -- immunology
Allergy and Immunology
MEDICAL -- Immunology.
Natural immunity.
Immunology.
Form Electronic book
Author Fujita, Takashi
LC no. 2012033875
ISBN 9781587066719
1587066718
9781587066580
1587066580