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Title Massive and irreparable rotator cuff tears from basic science to advanced treatments / Nuno Sampaio Gomes, Ladislav Kovačič, Frank Martetschläger, Giuseppe Milano, editors
Published Berlin, Germany : Springer, 2020

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Description 1 online resource (377 pages)
Contents Intro -- Foreword -- Preface -- Contents -- Part I: Basic Science -- 1: Massive and Irreparable Rotator Cuff Tears: Defining the Problem -- 1.1 Introduction -- 1.2 Structural Problem -- 1.2.1 Classifications of Massive Rotator Cuff Tears -- 1.2.2 Tear Initiation and Progression -- 1.3 Biological Problem -- 1.3.1 Healing -- 1.3.2 Atrophy, Fatty Infiltration, Retraction, and Loss of Elasticity -- 1.4 Biomechanical Problem -- 1.4.1 Tractive Forces -- 1.4.2 Shoulder Function and Pseudoparalysis -- 1.4.3 Decentralization, Glenohumeral Joint Pressure, and Osteoarthritis
1.5 Conclusion -- References -- 2: Biology of Rotator Cuff Injury and Repair -- 2.1 Histological Features -- 2.1.1 The Normal Tendon Tissue -- 2.1.2 The Pathological Tendon Tissue -- 2.1.3 Histological Findings of Rotator Cuff Tendinopathy -- 2.1.4 The Role of Hypercholesterelemia in Tendinopathy -- 2.2 Rotator Cuff Injury -- 2.2.1 Mechanical and Extrinsic Factors -- 2.2.1.1 Anatomy -- 2.2.1.2 Overuse -- 2.2.1.3 Cigarette Smoking -- 2.2.2 Biological Factors -- 2.2.2.1 The Role of Vascular Supply -- 2.2.2.2 The Role of Diabetes Mellitus -- 2.2.2.3 The Role of Thyroid Hormones
2.2.2.4 The Role of Cholesterol and Lipids -- 2.2.3 Genetic Factors -- 2.2.3.1 The Role of Apoptosis -- 2.3 Rotator Cuff Healing -- 2.3.1 The Tendon Repair Process -- 2.3.1.1 Inflammatory Phase -- 2.3.1.2 Proliferative Phase -- 2.3.1.3 Remodeling Phase -- 2.3.2 Patients' Factors Affecting Tendon Healing -- 2.3.2.1 Age -- 2.3.2.2 Cigarette Smoking -- 2.3.2.3 Endocrine Disorders and Hormones -- 2.3.3 Intraoperative Variables and Surgical Technique -- 2.3.4 Timing of Surgery and Rehabilitation -- 2.3.5 Predictive Models to Quantify Tendon Healing -- References
3: Biomechanics of Rotator Cuff Repair -- 3.1 Introduction -- 3.2 Biomechanics of the Intact Rotator Cuff -- 3.3 Biomechanics of the Intact Capsule -- 3.4 Biomechanics of the Ruptured Rotator Cuff -- 3.5 Biomechanics of Rotator Cuff Repairs -- 3.6 The Biomechanical Concept of Superior Capsule Reconstruction -- 3.7 Summary -- References -- 4: Re-rupture or Non-healing? Factors Determining an Unsuccessful Repair -- 4.1 Introduction -- 4.2 Patients' Age -- 4.3 Tear Size -- 4.4 Fatty Infiltration -- 4.4.1 Muscle Atrophy and Muscle Tendon Retraction -- 4.5 Compliance with Rehabilitation
4.6 Smoking -- 4.7 Manual Workers -- 4.8 Injections/Medication -- 4.9 Type of Repair -- 4.10 Orthobiologics -- 4.11 Hypercholesterolemia and Diabetes Mellitus -- 4.12 Discussion -- 4.13 Summary -- References -- 5: Biological Augmentation in Rotator Cuff Repair: Growth Factors -- References -- 6: Biological Augmentation in Rotator Cuff Repair: Cell Therapies -- 6.1 Mesenchymal Stem Cells (MSCs) -- 6.2 Bone Marrow-Derived Mesenchymal Stem Cells (BM-MSCs) -- 6.3 Muscle-Derived Mesenchymal Stem Cells (MD-MSCs) -- 6.4 Adipose-Derived Mesenchymal Stem Cells (AD-MSCs)
Summary This book offers a truly comprehensive overview of the understanding and treatment of massive and irreparable rotator cuff tears, a painful and disabling shoulder condition that continues to pose major challenges. A thorough examination of basic science issues and evidence lays the foundation for discussion of key controversies in the field and exposition of a practical approach to treatment in which the role of both conservative and surgical management is explained. Special insights are provided into the new biological and nonoperative approaches that are becoming increasingly popular among practitioners. All potential surgical techniques are described, from partial repair and tendon transfer, to the use of dedicated implants. In addition, the value of anesthesia and regional blocks, both during surgery and in the postoperative phase, is discussed. The concluding section addresses particularly complex scenarios and offers guidance on the management of treatment complications and failures. Written by leading international shoulder experts, the book will be of value for shoulder surgeons, rehabilitators, and other health care practitioners
Notes 6.5 Tendon-Derived Mesenchymal Stem Cells (TD-MSCs)
Print version record
Subject Shoulder joint -- Rotator cuff.
Rotator Cuff Injuries
Rotator Cuff
Orthopaedics & fractures.
Sports injuries & medicine.
Medical -- Orthopedics.
Medical -- Sports Medicine.
Rehabilitation.
Medical -- Physical Medicine & Rehabilitation.
Shoulder joint -- Rotator cuff.
Form Electronic book
Author Gomes, Nuno Sampaio, editor.
Kovačič, Ladislav, editor.
Martetschläger, Frank, editor.
Milano, Giuseppe (Orthopaedic surgeon)
ISBN 9783662611623
3662611627