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Title Semaphorins : receptor and intracellular signaling mechanisms / edited by R. Jeroen Pasterkamp
Published New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2007


Description 1 online resource (xiv, 147 pages) : illustrations
Series Advances in experimental medicine and biology ; v. 600
Advances in experimental medicine and biology ; v. 600
Contents The CRMP family of proteins and their role in Sema3A signaling / Eric F. Schmidt and Stephen M. Strittmatter -- GTPases in semaphorin signaling / Andreas W. Püschel -- Intracellular kinases in semaphorin signaling / Aminul Ahmed and Britta J. Eickholt -- Mical flavoprotein monooxygenases : structure, function and role in semaphorin signaling / Sharon M. Kolk and R. Jeroen Pasterkamp -- Signaling of secreted semaphorins in growth cone steering / Sangwoo Shim and Guo-li Ming -- Modulation of semaphorin signaling by IG superfamily cell adhesion molecules / Ahmad Bechara [and others] -- Proteoglycans as modulators of axon guidance cue function / Joris de Wit and Joost Verhaagen -- Semaphorin signals in cell adhesion and cell migration : functional role and molecular mechanisms / Andrea Casazza, Pietro Fazzari, and Luca Tamagnone -- Semaphorin signaling during cardiac development / Toshihiko Toyofuku and Hitoshi Kikutani -- Semaphorin signaling in vascular and tumor biology / Gera Neufeld [and others]
Summary The book summarizes our progress in understanding the receptor and intracellular signaling mechanisms utilized by a family of proteins called the semaphorins. Originally these protein were identified as ""axon guidance cues"" important for the formation of nerve tracts but now it is realized that semaphorins subserve several distinct functions in a multitude of organ systems. The purpose of this book is to summarize our knowledge and make it available as a useful and comprehensive tool for the scientific community. This book will both be interesting for people working in the field as well as c
Analysis neoplasms
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Semaphorins.
Cell receptors.
Cellular signal transduction.
Intercellular Signaling Peptides and Proteins -- physiology
Semaphorins -- physiology
Receptors, Cell Surface
Signal Transduction
Receptors, Cell Surface -- physiology
SCIENCE -- Life Sciences -- Biochemistry.
Cell receptors.
Cellular signal transduction.
Intercellular Signaling Peptides and Proteins -- physiology.
Semaphorins -- physiology.
Receptors, Cell Surface -- physiology.
Sciences de la vie.
Cell receptors
Cellular signal transduction
Form Electronic book
Author Pasterkamp, R. Jeroen
ISBN 9780387709567