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Title Modern applications of cycloaddition chemistry / edited by Paolo Quadrelli
Published Amsterdam : Elsevier, 2019

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Description 1 online resource (1 volume)
Contents Front Cover; Modern Applications of Cycloaddition Chemistry; Copyright Page; Contents; List of Contributors; Foreword; 1 Cycloaddition reactions for antiviral compounds; Cycloaddition: general aspects; Cycloaddition for antiviral compounds; The virus; Diels-Alder and hetero Diels-Alder reactions and the antivirals; Antivirals and 1,3-dipolar cycloaddition reactions; [2+2] Cycloaddition reaction for antiviral compounds; Acknowledgment; References; 2 Cycloaddition reactions for anticancer compounds; Cancer; Diels-Alder and hetero Diels-Alder reactions for anticancer compounds
Anticancer compounds through 1,3-dipolar cycloaddition reactionsAzides; Nitrones and nitrile oxides; Nitrile imines; Azomethine ylides; Anticancer compounds through [2+2] cycloaddition reactions; Acknowledgment; References; 3 Drug delivery and cycloaddition reactions; General aspects; Nucleic acids delivery; Inorganic structures; Organic structures; Sugar-based structures; Nonsugar structures; Small interfering RNA delivery; Delivery of antineoplastic agents; Doxorubicin delivery; Daunorubicin; Antimicrotubule agents (paclitaxel) delivery
Topoisomerase I inhibitors delivery (camptothecins derivatives)Antimetabolites delivery; Antibiotic drug delivery systems; Antiviral drug delivery systems; Miscellaneous drugs; Albendazole; Steroids: prednisolone; Proteins: antibody, peptides, vaccines; Simvastatin; Empty drug delivery systems; Vescicles; Nanoparticles; Microparticles; Macroscopic structures; Acknowledgment; References; 4 Natural strategies in cycloaddition reactions; Biosynthesis of spinosyn A; Pyrroindomycins biosynthesis; Biosynthesis of versipelostatin; Biosynthesis of abyssomicin C; Myceliothermophins biosynthesis
Biosynthesis of equisetinDecarboxylation of phenylacrylic acids catalyzed by ferulic acid decarboxylase; Debated cases; Biosynthesis of lovastatin; Biosynthesis of leporin C; Thiazolyl peptide biosynthesis; Biosynthesis of Ucs1025A; Biosynthesis of Sch 210972; Conclusion; References; 5 Cycloaddition reactions in material science; Cycloaddition reactions for materials synthesis; Polymers; Hydrogels and liquid crystal gels; Carbon-based materials; Other materials; Surface and interface modification; Cycloadditions under nonclassical reaction conditions; References; Index; Back Cover
Summary Modern Applications of Cycloaddition Chemistry examines this area of organic chemistry, with special attention paid to cycloadditions in synthetic and mechanistic applications in modern organic chemistry. While many books dedicated to cycloaddition reactions deal with the synthesis of heterocycles, general applications, specific applications in natural product synthesis, and the use of a class of organic compounds, this work sheds new light on pericyclic reactions by demonstrating how these valuable tools elegantly solve synthetic and mechanistic problems. The work examines how pericyclic reactions have been extensively applied to different chemistry areas, such as chemical biology, biological processes, catalyzed cycloaddition reactions, and more. This work will be useful for organic chemists who deal with organic chemistry, medicinal chemistry, agrochemistry and material chemistry.--Provided by publisher
Notes Print version record
Subject Ring formation (Chemistry)
Cyclization
SCIENCE -- Chemistry -- Organic.
Ring formation (Chemistry)
Form Electronic book
Author Quadrelli, Paolo, editor
ISBN 9780128152744
0128152745