| Description |
1 online resource (512 pages) |
| Contents |
Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- Contributors -- Abbreviations -- Part I: Normal Articular Cartilage -- 1: Structure and Function of Articular Cartilage -- 1.1 Introduction -- 1.2 Articular Cartilage Structure and Composition -- 1.2.1 Chondrocytes and Chondrons -- 1.2.2 Extracellular Matrix -- 1.2.2.1 Proteoglycans -- 1.2.2.2 Collagens -- 1.2.2.3 Non-Collagenous Proteins and Glycoproteins -- 1.2.3 Articular Cartilage Fluorescent Molecules -- 1.3 Articular Cartilage Heterogeneity and Compartmentalization |
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1.3.1 Immature Articular-Epiphyseal Cartilage Complex -- 1.3.1.1 Articular Cartilage Component -- 1.3.1.2 Epiphyseal Cartilage Component -- 1.3.2 Skeletally Mature Articular Cartilage Zones -- 1.3.2.1 Zone 1: Superficial Zone -- 1.3.2.2 Zone 2: Middle Zone -- 1.3.2.3 Zone 3: Deep Zone -- 1.3.2.4 Tidemark -- 1.3.2.5 Zone 4: Zone of Calcified Cartilage -- 1.3.3 Macromolecular Variation of Uncalcified Articular Cartilage Zones -- 1.3.4 Articular Cartilage Extracellular Matrix and Chondrocyte Microenvironment -- 1.3.4.1 Pericellular Matrix -- 1.3.4.2 Territorial Matrix |
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1.3.4.3 Interterritorial Matrix -- 1.4 Function of Knee Articular Cartilage -- 1.4.1 Function Related to Structure of Articular Cartilage Components -- 1.4.2 Function of Articular Cartilage Zones -- 1.4.3 Function of Chondrocytes and Chondrons -- 1.4.4 Concept of Knee Loading During Walking -- 1.4.5 Role of Articular Cartilage Macromolecules in Joint Biomechanics -- 1.4.6 Osmotic Stress and Articular Cartilage Matrix Composition -- 1.5 Knee Lubrication -- 1.5.1 Endogenous Lubricants On Articular Cartilage Surface -- 1.5.1.1 Proteins -- 1.5.1.2 Phospholipids |
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1.5.1.3 Glycosaminoglycans -- 1.5.2 Synergy of Molecular Lubricants -- 1.5.3 Deficiency of Molecular Lubricants -- 1.5.4 Lubrication Mechanisms (Applicable to Human Knee) -- 1.5.4.1 Boundary and Contact Lubrication Mechanism -- 1.5.4.2 Fluid-Film Lubrication -- Squeeze-Film Lubrication -- Hydrodynamic Lubrication -- 1.5.4.3 Elastohydrodynamic Lubrication -- 1.5.4.4 Application of Lubrication Mechanisms During "Walk Cycle" Phases -- 1.5.4.5 Failure of Lubrication Mechanism (Injury, Aging, Disease and Post-Cartilage Repair) -- 1.6 Conclusions -- References |
| Summary |
Covering both pediatric and adult populations, this comprehensive text covers the diverse topics related to the health, disease and therapy of articular cartilage of the knee, from basic principles to future directions for research. This vast array of information is arranged into eight sections, encompassing a number of relevant disciplines and covering, in turn, normal articular cartilage, aging and degeneration, evaluation and assessment, non-surgical approaches, surgical approaches, qualitative and quantitative assessment of repair, research into cartilage repair and engineering, and future prospects for therapy. Each chapter is amply referenced and self-contained for independent study and reference. Scoring systems for knee cartilage assessment are included in four appendices as well, rounding out the presentation. A multidisciplinary collection of basic, translational and clinical material, Articular Cartilage of the Knee is a singular resource for orthopedic surgeons, rheumatologists, pathologists, scientists, tissue engineers and the broad spectrum of clinical professionals working with articular cartilage and its disorders |
| Notes |
2.4.1.3 Wnt Family |
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Online resource; title from digital title page (viewed on June 04, 2020) |
| Subject |
Articular cartilage -- Diseases.
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Knee -- Diseases.
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Cartilage -- anatomy & histology
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Knee -- anatomy & histology
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Rheumatology.
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Sports injuries & medicine.
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Orthopaedics & fractures.
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Medical -- Rheumatology.
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Medical -- Sports Medicine.
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Medical -- Orthopedics.
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Articular cartilage -- Diseases
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Knee -- Diseases
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| Form |
Electronic book
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| Author |
Gahunia, Harpal K.
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Gross, Allan E.
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Pritzker, Kenneth P. H
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Babyn, Paul S.
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Murnaghan, Lucas
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| ISBN |
1493975870 |
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9781493975877 |
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