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Title Synthetic nucleic acids as inhibitors of gene expression : mechanisms, applications, and therapeutics implications / edited by Levon Michael Khachigian
Published Boca Raton : CRC Press, [2005]


Location Call no. Vol. Availability
 W'PONDS  572.8 Kha/Sna  AVAILABLE
Description 182 pages : illustrations (some color) ; 25 cm
Summary "This book brings together timely, authoritative reviews by renowned international leaders in the fields of ribozymes, RNA interference, DNAzymes and oligonucleotide decoys, with emphasis on biochemistry and translational research. The chapters on ribozymes include discussions of ribozyme subtypes, structure-function aspects, and therapeutic applications: those on DNAzymes, their various subtypes, kinetics and biochemistry, and applications in target validation. Finally, the mechanisms and multiple therapeutic applications of double-stranded oligonucleotide decoys are described." "For readers ranging from graduate students to researchers seeking target validation for pharmaceuticals to clinicians seeking innovative cancer, cardiovascular and other therapies, no resource is more complete and up to date."--BOOK JACKET
Bibliography Includes bibliographical references and index
Subject Catalytic RNA.
Repressors, Genetic.
Genetic regulation.
Genre/Form Biographies.
Author Khachʻikyan, L. S. (Levon Stepʻani), 1918-1982.
LC no. 2004054474
ISBN 0849330254 acid-free paper