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Book Cover
E-book
Author Leung, Po Sing.

Title The renin-angiotensin system : current research progress in the pancreas, the RAS in the pancreas / Po Sing Leung
Published Dordrecht ; New York : Springer, ©2010

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Description 1 online resource (xvi, 207 pages) : illustrations
Series Advances in experimental medicine and biology ; v. 690
Advances in experimental medicine and biology ; v. 690.
Contents Overview of the pancreas -- Physiology of the pancreas -- Common pancreatic disease -- Circulating RAS -- Local RAS -- Pancreatic RAS -- Basic techniques for pancreatic research -- Current research of the RAS in diabetes mellitus -- Current research concerning the RAS in pancreatic stem cells -- Current research of the RAS in pancreatitis and pancreatic cancer
Summary The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: - Structure, physiology and disease of the pancreas - Biochemistry and physiology of the pancreatic renin-angiotensin system - RAS in diabetes, stem cells and pancreatitis This book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field
Bibliography Includes bibliographical references and index
In Springer eBooks
Subject Renin-angiotensin system.
Pancreas.
Pancreas -- Diseases.
Pancreas
Renin-Angiotensin System
Pancreatic Diseases
Biomedical Research
MEDICAL -- Pharmacology.
Biomédecine.
Sciences de la vie.
Pancreas -- Diseases
Pancreas
Renin-angiotensin system
Form Electronic book
ISBN 9789048190607
9048190606
9789048190591
9048190592