| Description |
1 online resource (xvii, 462 pages) : illustrations |
| Series |
Factsbook series |
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Factsbook series.
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| Contents |
Machine generated contents note: Sect. I Introductory Chapters -- Ch. 1 General organization of nuclear receptors -- Ch. 2 DNA recognition by nuclear receptors -- Ch. 3 Ligand binding -- Ch. 4 Molecular mechanisms of transcriptional regulation -- Ch. 5 RXR subordination in heterodimers -- Ch. 6 Antagonist action -- Ch. 7 Nuclear receptors: platforms for multiple signal integration -- Ch. 8 Deregulation in disease and novel therapeutic targets -- Ch. 9 Genes and evolution -- Ch. 10 Conclusions -- Sect. II Nuclear Receptors -- TR [NR1A] -- RAR (NR1B) -- PPAR (NR1C) -- Rev-erb (NR1D, E and G) -- ROR (NR1F) -- EcR (NR1H1) -- LXR (NR1H2 and 3) -- FXR (NR1H4) -- VDR (NR111) -- PXR (NR112) -- CAR (NR113 and 4) -- DHR96, DAF12 (NR1J1) -- HNF4 (NR2A) -- RXR (NR2B) -- TR2, TR4 (NR2C and D) -- TLL (NR2E) -- COUP-TF (NR2F) -- ER (NR3A) -- ERR (NR3B) -- GR (NR3C1) -- MR (NR3C2) -- PR (NR3C3) -- AR (NR3C4) -- NGFIB (NR4A) -- SF-1 and FTZ-F1 (NR5A and B) -- GCNF (NR6A) -- Knirps (NR0A1, 2 and 3) -- Odr-7 (NR0A4) -- DAX1, SHP (NR0B) |
| Summary |
The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure Isolation DNA binding properties Ligands Expression Target genes Knockouts Disease association Gene structure, promoter and isoforms Chromosomal location Amino acid sequences Key references |
| Analysis |
celkernen |
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nuclei |
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receptoren |
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receptors |
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transcriptie |
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transcription |
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transcriptiefactoren |
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transcription factors |
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genetische regulatie |
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genetic regulation |
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Nucleic Acids |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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English |
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Print version record |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Subject |
Nuclear receptors (Biochemistry) -- Handbooks, manuals, etc
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Nuclear receptors (Biochemistry)
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Receptors, Cytoplasmic and Nuclear
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SCIENCE -- Life Sciences -- Molecular Biology.
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Nuclear receptors (Biochemistry)
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Biologia molecular.
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Receptores.
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Fisiologia.
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Kernrezeptor
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| Genre/Form |
handbooks.
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Handbooks and manuals
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Handbooks and manuals.
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Guides et manuels.
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| Form |
Electronic book
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| Author |
Gronemeyer, H. (Hinrich)
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| ISBN |
9780124377356 |
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0124377351 |
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9780080537801 |
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0080537804 |
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1281033235 |
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9781281033239 |
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9786611033231 |
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6611033238 |
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