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Book Cover
Author Laudet, Vincent.

Title The nuclear receptor : factsbook / Vincent Laudet and Hinrich Gronemeyer
Published San Diego : Academic Press, ©2002


Description 1 online resource (xvii, 462 pages) : illustrations
Series Factsbook series
Factsbook series.
Contents Machine generated contents note: Sect. I Introductory Chapters -- Ch. 1 General organization of nuclear receptors -- Ch. 2 DNA recognition by nuclear receptors -- Ch. 3 Ligand binding -- Ch. 4 Molecular mechanisms of transcriptional regulation -- Ch. 5 RXR subordination in heterodimers -- Ch. 6 Antagonist action -- Ch. 7 Nuclear receptors: platforms for multiple signal integration -- Ch. 8 Deregulation in disease and novel therapeutic targets -- Ch. 9 Genes and evolution -- Ch. 10 Conclusions -- Sect. II Nuclear Receptors -- TR [NR1A] -- RAR (NR1B) -- PPAR (NR1C) -- Rev-erb (NR1D, E and G) -- ROR (NR1F) -- EcR (NR1H1) -- LXR (NR1H2 and 3) -- FXR (NR1H4) -- VDR (NR111) -- PXR (NR112) -- CAR (NR113 and 4) -- DHR96, DAF12 (NR1J1) -- HNF4 (NR2A) -- RXR (NR2B) -- TR2, TR4 (NR2C and D) -- TLL (NR2E) -- COUP-TF (NR2F) -- ER (NR3A) -- ERR (NR3B) -- GR (NR3C1) -- MR (NR3C2) -- PR (NR3C3) -- AR (NR3C4) -- NGFIB (NR4A) -- SF-1 and FTZ-F1 (NR5A and B) -- GCNF (NR6A) -- Knirps (NR0A1, 2 and 3) -- Odr-7 (NR0A4) -- DAX1, SHP (NR0B)
Summary The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure Isolation DNA binding properties Ligands Expression Target genes Knockouts Disease association Gene structure, promoter and isoforms Chromosomal location Amino acid sequences Key references
Analysis celkernen
transcription factors
genetische regulatie
genetic regulation
Nucleic Acids
Bibliography Includes bibliographical references and index
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Print version record
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
Subject Nuclear receptors (Biochemistry) -- Handbooks, manuals, etc
Nuclear receptors (Biochemistry)
Receptors, Cytoplasmic and Nuclear
SCIENCE -- Life Sciences -- Molecular Biology.
Nuclear receptors (Biochemistry)
Biologia molecular.
Genre/Form handbooks.
Handbooks and manuals
Handbooks and manuals.
Guides et manuels.
Form Electronic book
Author Gronemeyer, H. (Hinrich)
ISBN 9780124377356