Title Stochastic dynamics of reacting biomolecules / Werner Ebeling, Lutz Schimansky-Geier, Yuri M. Romanovsky

Published River Edge, N.J. : World Scientific, ©2002

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Description 1 online resource (xxiii, 318 pages) : illustrations Contents Ch. 1. Introduction to the reaction theory and cluster dynamics of enzymes / W. Ebeling, A. Netrebko, Yu. Romanovsky -- ch. 2. Tools of stochastic dynamics / L. Schimansky-Geier and P. Talkner -- ch. 3. Motion of test particles in a 2-d potential landscape / O.A. Chichigina, A.V. Netrebko, and N.V. Netrebko -- ch. 4. Microscopic simulations of activation and dissociation / W. Ebeling [and others] -- ch. 5. Excitations on rings of molecules / A. Chetverikov [and others] -- ch. 6. Fermi resonance and Kramers problem in 2-d force field / S.V. Kroo [and others] -- ch. 7. Molecular scissors. Cluster model of acetylcholinesterase / A. Yu. Chikishev [and others] -- ch. 8. Dynamics of proton transfer in the active site of chymotrypsin / A. Yu. Chikishev, B.A. Grishanin and E.V. Shuvalova -- ch. 9. On the damping of cluster oscillations in protein molecules / A. Yu. Chikishev, A.V. Netrebko, and Yu. M. Romanovsky -- ch. 10. Protein dynamics and new approaches to the molecular mechanisms of protein functioning / K.V. Shaitan -- ch. 11. Conclusions Summary This is a book about the physical processes in reacting complex molecules, particularly biomolecules. In the past decade scientists from different fields such as medicine, biology, chemistry and physics have collected a huge amount of data about the structure, dynamics and functioning of biomolecules. Great progress has been achieved in exploring the structure of complex molecules. However, there is still a lack of understanding of the dynamics and functioning of biological macromolecules. In particular this refers to enzymes, which are the basic molecular machines working in living systems. This book contributes to the exploration of the physical mechanisms of these processes, focusing on critical aspects such as the role of nonlinear excitations and of stochastic effects. An extensive range of original results has been obtained in the last few years by the authors, and these results are presented together with a comprehensive survey of the state of the art in the field Bibliography Includes bibliographical references and index Notes English Print version record Subject Physical biochemistry. Stochastic processes. Biomolecules -- Reactivity Biomolecules -- Structure Biochemistry. Chemistry, Physical and theoretical. Mathematical models. Biochemistry Stochastic Processes Enzymes -- chemistry Chemistry, Physical Models, Theoretical biochemistry. physical chemistry. mathematical models. SCIENCE -- Life Sciences -- Biochemistry. Mathematical models Chemistry, Physical and theoretical Biochemistry Biomolecules -- Reactivity Biomolecules -- Structure Physical biochemistry Stochastic processes Form Electronic book Author Schimansky-Geier, Lutz, 1950- Romanovsky, Yuri M. ISBN 9789812795434 981279543X 9789812381620 9812381627 1281935832 9781281935830 9786611935832 6611935835

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