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Title Proteases and cancer : methods and protocols / edited by Salvatore Santamaria
Published New York, NY : Humana Press, [2024]


Description 1 online resource (xii, 316 pages) : illustrations (chiefly color)
Series Methods in molecular biology, 1940-6029 ; 2747
Methods in molecular biology (Clifton, N.J.) ; 2747. 1940-6029
Summary This volume details bioinformatics analysis, biochemical assays, recombinant protein expression and purification, methods to investigate protease activity in cell-based, organoids and in vivo systems, proteomics, transcriptomics, machine learning and novel approaches to target dysregulated protease activity in cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Proteases and Cancer: Methods and Protocols aims to provide the scientific community with a diverse and representative collection of state-of-the-art methods to investigate the protean functions of proteases in cancer biology
Notes Includes index
Online resource; title from PDF title page (SpringerLink, viewed December 6, 2023)
Subject Proteolytic enzymes -- Laboratory manuals
Cancer -- Research -- Methodology
Genre/Form Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Santamaria, Salvatore, editor
ISBN 9781071635896