Title A metaheuristic approach to protein structure prediction : algorithms and insights from fitness landscape analysis / Nanda Dulal Jana, Swagatam Das, Jaya Sil

Published Cham : Springer, [2018]

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Description 1 online resource (xxix, 220 pages) : illustrations Series Emergence, Complexity and Computation, 2194-7287 ; 31 Emergence, complexity and computation ; 31. 2194-7287 Contents Metaheuristic Protein Structure Prediction-An Overview -- Related Works -- Continuous Landscape Analysis using Random Walk Algorithm -- Landscape Characterization and Algorithms Selection for the PSP Problem -- The Levy distributed Parameter Adaptive Metaheuristic Algorithm for Protein Structure Prediction -- Protein Structure Prediction using Improved Variants of Metaheuristic Algorithms -- Hybrid Metaheuristic Approach for Protein Structure Prediction -- Conclusions and Future Research Summary This book introduces characteristic features of the protein structure prediction (PSP) problem. It focuses on systematic selection and improvement of the most appropriate metaheuristic algorithm to solve the problem based on a fitness landscape analysis, rather than on the nature of the problem, which was the focus of methodologies in the past. Protein structure prediction is concerned with the question of how to determine the three-dimensional structure of a protein from its primary sequence. Recently a number of successful metaheuristic algorithms have been developed to determine the native structure, which plays an important role in medicine, drug design, and disease prediction. This interdisciplinary book consolidates the concepts most relevant to protein structure prediction (PSP) through global non-convex optimization. It is intended for graduate students from fields such as computer science, engineering, bioinformatics and as a reference for researchers and practitioners Bibliography Includes bibliographical references Notes Online resource; title from PDF title page (ProQuest Ebook Central, viewed July 3, 2021) In Springer eBooks Subject Proteins -- Structure -- Mathematical models Proteins -- Structure -- Computer simulation Proteins -- Conformation. Mathematical models. Computer simulation. Digital computer simulation. Protein Conformation Models, Theoretical Computer Simulation mathematical models. simulation. SCIENCE -- Life Sciences -- Biochemistry. Proteins -- Structure -- Mathematical models Proteins -- Structure -- Computer simulation Artificial intelligence Computational complexity Computational intelligence Engineering Proteins Form Electronic book Author Das, Swagatam, author. Sil, Jaya, author ISBN 9783319747750 3319747754

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