1. The crystalline state and its study -- 2. Vector analysis and complex algebra -- 3. Crystal systematics -- 4. Waves and electromagnetic radiation -- 5. Fourier transforms and convolutions -- 6. Diffraction -- 7. Diffraction from one-dimensional obstacles -- 8. Diffraction from a three-dimensional lattice -- 9. The contents of the unit cell -- 10. Experimental techniques: sample preparatio -- 11. Experimental techniques: data collection and analysis -- 12. The Phase problem and the Patterson function -- 13. Molecular replacement -- 14. Solving the phase problem experimentally -- 15. Refinement -- 16. Complementary diffraction methods
Summary
Information derived from X-ray crystal structures of biological molecules allows us to explain their functions in living organisms and to develop drugs to treat disease. This book describes the principles and practice of X-ray diffraction as a key technique at the forefront of new discoveries in biology and medicine
