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Title RNA structure and folding : biophysical techniques and prediction methods / edited by Dagmar Klostermeier and Christian Hammann
Published Berlin : Walter de Gruyter, [2013]


Description 1 online resource (408 pages)
Contents Optical spectroscopy and calorimetry / Dagmar Klostermeier and Christian Hammann -- Footprinting methods for mapping RNA-protein and RNA-RNA interactions / Mélodie Duval [and others] -- Chemical approaches to the structural investigation of RNA in solution / Mark Helm -- Bioorthogonal modifications and cycloaddition reactions for RNA chemical biology / Claudia Höbartner, Lea Büttner, and Fatemeh Javadi-Zarnaghi -- Analysis of RNA conformation using comparative gel electrophoresis / David M.J. Lilley -- Virus RNA structure deduced by combining x-ray diffraction and atomic force microscopy / Alexander McPherson -- Investigating RNA structure and folding with optical tweezers / Mathilde Bercy [and others] -- Fluorescence resonance energy transfer as a tool to investigate RNA structure and folding / Airat Gubaev and Dagmar Klostermeier -- RNA studies by small angle x-ray scattering (SAX) in solution / Alexey G. Kikhney, Sebastian Doniach, and Dmitri I. Svergun -- Integrative structure-function analysis of large nucleoprotein complexes / Jean-François Ménétret [and others] -- Structure and conformational dynamics of RNA determined by pulsed EPR / Ivan Krstic -- NMR-based characterization of RNA structure and dynamics / Christina R. Mozes and Mirko Hennig -- Crystallization of RNA for structure determination by x-ray crystallography / Adrian R. Ferré-D'Amaré -- RNA structure prediction / Gerhard Steger and Robert Giegerich -- Analyzing, searching, and annotating recurrent RNA three-dimensional motifs
Summary "While structure-function relationships of proteins have been studied for a long time, structural studies of RNA face additional challenges. Nevertheless, with the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. This volume provides an introduction into techniques to assess structure and folding of RNA. Each chapter explains the theoretical background of one technique, and illustrates possibilities and limitations in selected application examples"--Provided by publisher
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject RNA -- Analysis
RNA -- Structure
Protein folding.
RNA -- chemistry
Nucleic Acid Conformation
Protein Interaction Mapping
RNA Folding
SCIENCE -- Life Sciences -- Biochemistry.
Protein folding
RNA -- Analysis
RNA -- Structure
Form Electronic book
Author Klostermeier, Dagmar, editor.
Hammann, Christian, editor.
ISBN 9783110284959