Translating STAT inhibitors from the lab to the clinic / Suhu Liu and David Frank -- Historical development of STAT3 inhibitors and early results in clinical trials / Chao-Lan Yu, Richard Jove, and James Turkson -- STAT3 inhibitors in cancer: a comprehensive update / Uddalak Bharadwaj, Moses M. Kasembeli, and David J. Tweardy -- Targeting upstream Janus kinases / Parisa Rasighaemi and Alister C. Ward -- Inhibitors of upstream inducers of STAT activation / Janani Kumar -- Index