A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES
A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES
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Protease Nexins : Alzheimer's disease : methods and protocols / edited by Nigel M. Hooper
A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme
A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme
Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES), conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES), and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES)
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Proteasome Endopeptidase Complex : Proteostasis and disease : from basic mechanisms to clinics / Rosa Barrio, James D. Sutherland, Manuel S. Rodriguez, editors
protección complementaria. : Employment and health benefits : a connection at risk / Committee on Employer-Based Health Benefits, Division of Health Care Services, Institute of Medicine ; Marilyn J. Field and Harold T. Shapiro, editors
1993
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Protección de datos : Data storage for social networks : a socially aware approach / Duc A. Tran
protección de los datos. : Knowledge societies --in a nutshell : information technology for sustainable development / Andreas Credé & Robin Mansell for the United Nations Commission on Science and Technology for Development and the International Development Research Centre
1998
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Protección de menores -- España : El interés superior del menor y las medidas civiles a adoptar en supuestos de violencia de género / Virginia Múrtula Lafuente
proteccionismo. : Taking trade to the streets : the lost history of public efforts to shape globalization / Susan Ariel Aaronson ; with forewords by Pat Choate and I.M. Destler
2001
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Protect Public Art! : Protecting public art : community involement in the in the management of outdoor cultural objects / Edwina M. d'Apice
Protected areas -- Brazil. : Tourism and protected areas in Brazil : challenges and perspectives / André de Almeida Cunha, Teresa Cristina Magro-Lindenkamp and Stephen Ford McCool, editors
