Limit search to available items
Book Cover

Title New mechanisms for tissue-selective estrogen-free contraception / H.B. Croxatto [and others], editors
Published Berlin ; New York : Springer, ©2005


Description 1 online resource (xii, 261 pages) : illustrations (some color)
Series Ernst Schering Research Foundation workshop, 0947-6075 ; 52
Ernst Schering Research Foundation workshop ; 52. 0947-6075
Contents Progesterone Receptors and Opportunities for Contraception -- Reproductive Tissue-Selective Actions of Progesterone Receptors -- The Progesterone Receptor/Estradiol Receptor Association and the Progestin-Triggered S-Phase Entry -- Endometrial Morphology and Progestogens -- Role of Progesterone in the Structural and Biochemical Remodeling of the Primate Endometrium -- Effects of Progestogens on Endometrial Maturation in the Implantation Phase -- Gene Expression During the Implantation Window: Microarray Analysis of Human Endometrial Samples -- Role of EBAF/Lefty in Implantation and Uterine Bleeding -- Mechanisms Underlying Menstrual Bleeding Disturbances with Progestogens -- Human Endocervical Mucins -- Fallopian Tube Physiology: Preliminaries to Monospermic Fertilization and Cellular Events Postfertilization
Summary Combined oral contraceptives are the most convenient and accepted method of hormonal contraception. Nevertheless, the medical community and consumers constantly demand innovation, additional benefits during use and lower hormonal load despite the high safety profile of available products. At the Ernst Schering Research Foundation Workshop 52, new perspectives and mechanisms for tissue-selective, estrogen-free contraception were discussed. The aim of the workshop was to bring together experts in the field of molecular and pharmacodynamic action of progestins with clinicians and medical experts to discuss potential medical endpoints, physiological reactions and (bio)marker useful describing the tissue selectivity and the contraceptive action of new progestins in different target organs. A major factor for successful realization of these new concepts is a deeper understanding of local pharmacological responses to progestins in general and to new progestins in particular
Analysis geneeskunde
public health
reproductive organs
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references
Notes English
Print version record
In Springer e-books
Subject Contraceptives.
Progestins -- pharmacology
Receptors, Progesterone -- physiology
Contraceptive Agents, Female -- pharmacology
Endometrium -- drug effects
Genre/Form Electronic books
proceedings (reports)
Conference papers and proceedings
Conference papers and proceedings.
Actes de congrès.
Form Electronic book
Author Croxatto, H. B. (Horacio B.)
ISBN 9783540271475