Uniform Title Prion diseases (Liberski) Title Prion diseases / edited by Pawel P. Liberski

Published New York, NY : Human Press imprint is published by Springer Nature, [2017] ©2017

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Description 1 online resource (xv, 304 pages) : illustrations (some color), color portraits Series Neuromethods, 1940-6045 ; 129 Neuromethods ; 129. 0893-2336 Contents Kuru: introduction to prion diseases / Paweł P. Liberski, Agata Gajos -- Anthropological methods used in kuru research / Shirley Lindenbaum -- Nonhuman primates in research on transmissible spongiform encephalopathies / David M. Asher, Pedro Piccardo, Luisa Gregori -- Clinical features and diagnosis of human prion diseases / Richard Knight -- Neuropathology, immunohistochemistry, and biochemistry in human prion diseases / Diane L. Ritchie, James W. Ironside -- Subcellular and molecular changes associated with abnormal PrP accumulation in brain and viscera of classical and atypical prion diseases / Martin Jeffrey, Gillian McGovern -- Electron microscopy of prion diseases / Paweł P. Liberski -- Cell death and autophagy in prion diseases / Pawel P. Liberski -- Methods for isolation of Spiroplasma sp. from prion-positive eye tissues of sheep affected with terminal scrapie / Frank O. Bastian -- Detection and diagnosis of prion diseases using RT-QuIC: an update / Byron Caughey, Christina D. Orru, Bradley R. Groveman, Matilde Bongianni [and others] -- Analysis of charge isoforms of the scrapie prion protein using two-dimensional electrophoresis / Elizaveta Katorcha, Ilia V. Baskakov -- Exosomes in prion diseases / Alexander Hartmann, Hermann Altmeppen, Susanne Krasemann, Markus Glatzel -- Synthetic mammalian prions / Fabio Moda, Edoardo Bistaffa, Joanna Narkiewicz, Giulia Salzano, Giuseppe Legname -- Biomarkers in cerebrospinal fluid / Joanna Gawinecka, Matthias Schmitz, Inga Zerr -- The use of transgenic and knockout mice in prion research / Abigail B. Diack, Jean C. Manson -- Transgenic mouse models of prion diseases / Julie Moreno, Glenn C. Telling Summary "This volume provides comprehensive information and detailed laboratory protocols used in the study of prion diseases. The chapters in this book cover topics such as: electron microscopy, neuropathology, immunohistochemistry, and immune-gold electron microscopy of prion diseases. Chapters also provide readers with detailed information about kuru, the clinical description of prion diseases, and the detection of prion protein and biomarkers. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Prion Diseases is a valuable resource for researchers and scientists in the exciting and rapidly growing field of prion disease research"--Publisher's description Bibliography Includes bibliographical references and index Notes Online resource; title from resource home page (SpringerLink, viewed August 22, 2017) Subject Prion diseases -- Laboratory manuals Prion Diseases Prions -- isolation & purification Prion diseases Form Electronic book Genre/Form Laboratory manuals Laboratory manuals. Manuels de laboratoire. ISBN 9781493972111 1493972111 9781493972098 149397209X

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