Title Lung development and regeneration / edited by Donald J. Massaro, Gloria DeCarlo Massaro, Pierre Chambon

Published New York : Marcel Dekker, ©2004

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Description 1 online resource (xiv, 593 pages) : illustrations Series Lung biology in health and disease ; v. 190 Lung biology in health and disease ; v. 190. Contents I. Diseases: bronchopulmonary dysplasia (BPD) and chronic obstructive pulmonary disease (COPD): Arrested alveolar development in bronchopulmonary dysplasia -- Bronchopulmonary dysplasia in the postsurfactant era -- What is chronic obstructive pulmonary disease? -- Small airways disease in chronic obstructive pulmonary disease -- Alveolar and bronchiolar inflammation in COPD -- Pathophysiological basis for treatment of chronic obstructive pulmonary disease -- Clinical approaches for evaluating retinoids as a treatment for human emphysema -- II. Technological and theoretical foundations for studies aimed at remedial therapy: Detecting differentially expressed genes by differential display -- Expression profiling as a tool for diagnosis and pathway discovery: experimental design and technical considerations -- Plasticity of circulating adult stem cells -- The mechanical and cytoskeletal basis of lung morphogenesis -- III. Comparative lung structure and mechanics: Morphogenesis of the mammalian lung: aspects of structure and extracellular matrix -- Structure and function of nonmammalian vertebrate lungs -- IV. Branching morphogenesis: Lung branching morphogenesis: potential for regeneration of small conducting airways -- V. The gas-exchange region: Apoptosis and emphysema -- Genetic analysis of emphysema and animal models of COPD -- Pulmonary alveoli: development, structural stability, and regeneration -- Molecular response to pneumonectomy -- Pulmonary limitations to exercise performance: the effects of health ageing and COPD -- Pulmonary adaptation to sustained changes in metabolic rate Summary This reference compiles the most current technical and biological data available to survey the state-of-science in the care and management of patients with bronchopulmonary dysplasia, COPD, and other forms of lung disease-tracking the initiation and progression of processes that cause airway obstruction, the biologic and physiological abnormalities that characterize COPD, and the potential reversibility of the inflammatory response in COPD for improved patient diagnosis and treatment Bibliography Includes bibliographical references and index Notes English Print version record Subject Lungs -- Growth Lungs -- Diseases. Bronchopulmonary dysplasia. Lung -- growth & development Lung Diseases Bronchopulmonary Dysplasia Lung -- embryology Lung Diseases, Obstructive MEDICAL -- Physiology. SCIENCE -- Life Sciences -- Human Anatomy & Physiology. Bronchopulmonary dysplasia Lungs -- Diseases Lungs -- Growth Poumon -- croissance et développement. Poumon -- embryologie. Bronchopneumopathies obstructives. Dysplasie bronchopulmonaire. Lunge. Lungenkrankheit. Pathophysiologie. Wachstum (Biologie) Form Electronic book Author Massaro, Donald, 1932- Massaro, Gloria DeCarlo Chambon, Pierre ISBN 1420030531 9781420030532 0429115865 9780429115868 1280610050 9781280610059 9786610610051 6610610053

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