| Description |
1 online resource (246 pages) : illustrations (some color) |
| Series |
Molecular biology intelligence unit |
|
Molecular biology intelligence unit (Unnumbered)
|
| Contents |
Enzymes in poly(ADP-ribose) metabolism / Ralph G. Meyer [and others] -- PARP-2: structure-function relationship / Valørie Schreiber [and others] -- Targeting the poly(ADP-ribose) glycohydrolase (PARG) gene in mammals / Ulrich Cortes and Zhao-Qi Wang -- DNA damage signaling through poly(ADP-ribose) / Maria Malanga and Felix R. Althaus -- Roles of poly(ADP-ribose) metabolism in the regulation of centrosome duplication and in the maintenance of neuronal integrity / Masanao Miwa [and others] -- Functional interactions of PARP-1 with p53 / Rafael Alvarez-Gonzalez [and others] -- Dynamic interaction between PARP-1, PCNA and p21waf1/cip1 / Ennio Prosperi and A. Ivana Scovassi -- Parp-1 as novel coactivator of NF-kB in inflammatory disorders / Paul O. Hassa and Michael O. Hottiger -- PARP and epigenetic regulation / Paola Caiafa -- PARP and the release of apoptosis-inducing factor from mitochondria / Suk Jin Hong, Ted M. Dawson and Valina L. Dawson -- Genome degradation by DNAS1L3 endonuclease: a key PARP-1-regulated event in apoptosis / A. Hamid Boulares, Alexander G. Yakovlev and Mark E. Smulson |
|
NAD-metabolism and regulatory functions / Mathias Ziegler -- PARP-1 and the shape of cell death / Laszlø Virøg -- Poly(ADP-ribose) polymerase (PARP) and excitotoxicity / Domenico E. Pellegrini-Giampietro, Alberto Chiarugi and Flavio Moroni -- Poly(ADP-ribose) polymerase and ischemia-reperfusion injury / Prabal K. Chatterjee and Christoph Thiemermann -- Role of poly(ADP-ribose) polymerase activation in the pathogenesis of inflammation and circulatory shock / Csaba Szabø -- Role of poly-ADP-ribosylation in cancer development / Mitsuko Masutani [and others] -- PARP inhibitors and cancer therapy / Nicola J. Curtin -- Poly(ADP-ribosyl)ation and aging / Sascha Beneke and Alexander Bürkle |
| Summary |
Comprises 19 chapters written by leading international experts in the field. Also, bibliography is given in each chapter |
| Bibliography |
Includes bibliographical references and index |
| Subject |
ADP-ribosylation.
|
|
Apoptosis.
|
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Poly(ADP-ribose) Polymerases -- metabolism
|
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Apoptosis
|
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Gene Expression Regulation, Enzymologic
|
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SCIENCE -- Life Sciences -- Biochemistry.
|
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Apoptosis.
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Gene Expression Regulation, Enzymologic.
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ADP-ribosylation.
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Poly (ADP-ribose) Polymerases -- metabolism.
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Biomédecine.
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Sciences de la vie.
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Apoptosis
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ADP-ribosylation
|
| Form |
Electronic book
|
| Author |
Bürkle, Alexander.
|
| ISBN |
0387333711 |
|
9780387333717 |
|
9780387360058 |
|
0387360050 |
|
9786611167479 |
|
6611167471 |
|
