| Description |
1 online resource (x, 305 pages) : illustrations |
| Series |
Special publication ; no. 256 |
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Special publication (Royal Society of Chemistry (Great Britain)) ; no. 256.
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| Contents |
The potential use of quality control data to validate pesticide residue method performance -- Optimism and evaluation of multi-residue methods for priority pesticide in drinking and related waters -- Validation of analytical data in a research and development environment -- Performance validation of a multi-residue method for 170 pesticides in kiwifruit -- Effects of sample processing on pesticide residues in fruit and vegetables -- Testing efficiency and uncertainty of sample processing using 14C-labelled chlorpyrifos : part 1, Description of the methodology -- Testing efficiency and uncertainty of sample processing using 14C-labelled chlorpyrifos, part 2 -- Testing the effect of sample processing and storage on the stability of residues -- AOAC International collaborative study on the determination of pesticide residue in nonfatty foods by supercritical fluid extraction and gas chromatography/mass spectrometry -- Validation of analytical methods-proving your methods is 'fit for purpose' -- Validation of a multi-residue method for analysis of pesticides in fruit, vegetables and cereals by a GC/MS iontrap system -- Development and validation of a generic gas chromatographic method for the determination of organophosphorous pesticide residues in various sample extracts -- Validation of gas chromatographic databases for qualitative identification of active ingredients of pesticide residues -- Estimation of significance of 'matrix-induced' chromatographic effects -- Worked example of validation of a multi-residue method -- EU guidance documents on redue analytical methods -- Guidelines for single-laboratory validation of analytical methods for trace-level concentrations of organic chemicals -- A critique on available in-house method validation documentation |
| Summary |
This product is not available separately, it is only sold as part of a set. There are 750 products in the set and these are all sold as one entity. Principles and Practices of Method Validation is an overview of the most recent approaches used for method validation in cases when a large number of analytes are determined from a single aliquot and where a large number of samples are to be analysed. Much of the content relates to the validation of new methods for pesticide residue analysis in foodstuffs and water but the principles can be applied to other similar fields of analysis. Different chromatographic methods are discussed, including estimation of various effects, eg. matrix-induced effects and the influence of the equipment set-up. The methods used for routine purposes and the validation of analytical data in the research and development environment are documented. The legislation covering the EU-Guidance on residue analytical methods, an extensive review of the existing in-house method validation documentation and guidelines for single-laboratory validation of analytical methods for trace-level concentrations of organic chemicals are also included. With contributions from experts in the field, any practising analyst dealing with method validation will find the examples presented in this book a useful source of technical information |
| Notes |
Proceedings of the Joint AOAC/FAO/IAEA/IUPAC International Workshop on the Principles and Practices of Method Validation held in November 1999 in Budapest, Hungary |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
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Print version record |
| Subject |
High performance liquid chromatography -- Congresses
|
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Pharmaceutical chemistry -- Methodology -- Evaluation -- Congresses
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Chemistry.
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SCIENCE -- Chemistry -- Analytic.
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Science.
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High performance liquid chromatography
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| Genre/Form |
Conference papers and proceedings
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| Form |
Electronic book
|
| Author |
Fajgelj, A. (Aleš)
|
|
Ambrus, Á. (Árpád)
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| ISBN |
9781847551757 |
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1847551750 |
|
