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Title Molecular diagnostics and treatment of pancreatic cancer : systems and network biology approaches / edited by Asfar S. Azmi
Published Amsterdam : Elsevier/AP, 2014


Description 1 online resource (xx, 446 pages) : illustrations (chiefly color)
Contents Epidemiology, Treatment, and Outcome of Pancreatic Cancer -- Advances in Primary Cell Culture of Pancreatic Cancer -- Multimodal Therapies for Pancreatic Cancer -- The Role of Notch Signaling Pathway in the Progression of Pancreatic Cancer -- Bioinformatics Analysis of Pancreas Cancer Genome in High-Throughput Genomic Technologies -- Statistical Analysis of High-Dimensional Data for Pancreatic Cancer -- Gene Expression Profiling in Pancreatic Cancer -- Genetic Susceptibility and Risk of Pancreatic Cancer -- Proteomics in Pancreatic Cancer Translational Research -- Proteomic Differences and Linkages between Chemoresistance and Metastasis of Pancreatic Cancer Using Knowledge-Based Pathway Analysis -- RNAi Validation of Pancreatic Cancer Antigens Identified by Cell Surface Proteomics -- The Significance of the Feedback Loops between Kras and Ink4a in Pancreatic Cancer -- Systems Biology of Pancreatic Cancer Stem Cells -- Characterizing the Metabolomic Effects of Pancreatic Cancer -- Prioritizing Diagnostic, Prognostic, and Therapeutic MicroRNAs in Pancreatic Cancer: Systems and Network Biology Approaches -- Integration of Protein Network Activation Mapping Technology for Personalized Therapy: Implications for Pancreatic Cancer -- Computational and Biological Evaluation of Radioiodinated Quinazolinone Prodrug for Targeting Pancreatic Cancer -- Systems and Network Pharmacology Strategies for Pancreatic Ductal Adenocarcinoma Therapy: A Resource Review
Summary Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Pancreas -- Cancer -- Molecular diagnosis
Pancreas -- Cancer -- Treatment
Pancreatic Neoplasms -- diagnosis
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Form Electronic book
Author Azmi, Asfar S.
ISBN 1306642345