| Description |
1 online resource : illustrations |
| Contents |
Front Cover; Advances in Pathobiology and Management of Paget's Disease of Bone; Copyright Page; Contents; List of Contributors; About the Editor; Preface; 1 Clinical Perspectives of Paget's Disease of Bone; Introduction; Natural History; Clinical Features and Complications; Diagnosis; Pathology; Biochemistry; Epidemiology; Secular Change in Paget's Disease; References; 2 Viral Etiology of Paget's Disease of Bone; Introduction; Paramyxo-Viral Etiology; Viral and Genetic Interactions; Acknowledgments; References; 3 Genetics of Paget's Disease of Bone; Introduction |
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880-01 PDB: A Disorder of Protein Conformation?Acknowledgments; References; 7 Osteosarcoma in Paget's Disease of Bone; Introduction; Epidemiology; Clinical Presentation; Histopathology; Treatment and Prognosis; The Progression From Normal Bone to Paget's Disease to Pagetic Osteosarcoma; Genes Differentially Expressed in Paget's Disease and Pagetic Osteosarcoma; Acknowledgments; References; 8 Paget's Disease of Bone: Prognosis and Complications; Introduction; Prognosis of Paget's Disease of Bone; Morbidity and Quality of Life; Mortality; Impact of Pharmacological Treatment of PDB on the Prognosis |
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880-01/(S SQSTM1/p62 as a Signaling Hub Orchestrating the Interplay Between NFκB, Keap1 and AutophagyReferences; 6 Early Onset Pagetic Disorders: Implications for Late-Onset Paget's Disease of Bone; Introduction; Early-Onset Pagetic Syndromes; RANK; Juvenile Paget's Disease; Osteoprotegerin; Multisystem Proteinopathy; Valosin-containing protein; Molecular Mechanisms Leading to Early-Onset Pagetic Disorders and Relevance for Late-onset PDB; Classic PDB: Association With Genes Involved in RANK Signaling and/or Osteoclast Formation; Classic PDB: Genes Involved in Protein Degradation Pathways |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (ScienceDirect, viewed May 10, 2016) |
| Subject |
Osteitis deformans.
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Osteitis deformans -- Treatment
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Osteitis Deformans
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Osteitis deformans
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| Form |
Electronic book
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| Author |
Reddy, Sakamuri V., editor
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| ISBN |
9780128096901 |
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012809690X |
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0128050837 |
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9780128050835 |
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