| Description |
1 online resource (222 pages) : illustrations |
| Series |
Topics in organometallic chemistry, 1436-6002 ; 17 |
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Topics in organometallic chemistry ; 17. 1436-6002
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| Contents |
Biological organometallic chemistry of B₁₂ / P.A. Butler, B. Kräutler -- Catalytic nickel-iron-sulfur clusters: from minerals to enzymes / A. Volbeda, J.C. Fontecilla-Camps -- Carbene complexes of heme proteins and iron porphyrin models / G. Simonneaux, P. Le Maux -- Organometallic receptors for biologically interesting molecules / K. Severin -- Ferrocene-peptide bioconjugates / T. Moriuchi, T. Hirao -- Medicinal properties of organometallic compounds / C.S. Allardyce, P.J. Dyson |
| Summary |
Bioorganometallic Chemistry has become a mature area of science and is comprehensively covered by leading experts in this book. Naturally occuring bioorganometallic complexes, such as vitamin B12 and recently discovered iron and nickel hydrogenases, including a possible role of the latter in the geochemical theory of the origin of life, are considered. The possible formation of carbene complexes of cytochrome P450 enzymes in various metabolisms of xenobiotics is also discussed. The bioorganometallic chemistry is considered to provide not only organometallic receptors such as polynuclear organometallic macrocycles for biologically interesting molecules but also ferrocene-peptide bioconjugates giving a peptidomimetic basis for protein folding. The medicinal properties of organometallic compounds are reviewed, with notable applications in the treatment and diagnosis of cancer and in the treatment of viral, fungal, bacterial and parasitic infections. Therefore the reader will get a balanced view of this rapidly developing and promising area |
| Bibliography |
Includes bibliographical references and indexes |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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English |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| In |
Springer e-books |
| Subject |
Organometallic compounds
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Biochemistry.
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Organic compounds.
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Inorganic compounds.
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Organometallic Compounds
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Organic Chemicals
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Inorganic Chemicals
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Chemicals and Drugs
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Biochemistry
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organometallic compound.
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biochemistry.
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organic compounds.
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Biochemistry.
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Organometallic Compounds -- chemistry.
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Organometallic Compounds -- pharmacology.
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Organometallic Compounds -- therapeutic use.
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Biochemie.
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Organometaalverbindingen.
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Organometallic compounds.
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Chimie.
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Science des matériaux.
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Organic compounds
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Inorganic compounds
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Biochemistry
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Organometallic compounds
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Biochemie.
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Organometaalverbindingen.
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| Form |
Electronic book
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| Author |
Simonneaux, Gérard
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Allardyce, C. S. (Claire S.)
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| LC no. |
2006924680 |
| ISBN |
354033047X |
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9783540330479 |
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9783540330493 |
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3540330496 |
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6611390146 |
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9786611390143 |
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