Title An approach to evaluate the effects of concomitant prescribing of opioids and benzodiazepines on veteran deaths and suicides / Committee on Developing a Protocol to Evaluate the Concomitant Prescribing of Opioids and Benzodiazepine Medications and Veteran Deaths and Suicides, Board on Health Care Services, Health and Medicine Division

Published Washington, DC : The National Academies Press, [2019]

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Description 1 online resource (1 PDF file (xii, 98 pages)) : color illustrations Series A consensus study report of the National Academies of Sciences, Engineering, Medicine Consensus study report. Contents Summary -- Introduction -- Specifying the target trial -- Observational emulation of the target trials and practical considerations Summary Introduction -- Specifying the target trial -- Observational emulation of the target trials and practical considerations "Opioid prescriptions for acute and chronic pain increased dramatically from the late 1990s into the current decade in both the civilian and the Department of Veterans Affairs and Department of Defense treatment environments. Similarly, prescriptions for benzodiazepines also increased significantly for anxiety and insomnia. Combinations of opioid and benzodiazepines have proben fatal when taken concurrently, with research demonstrating this phenomenon for nearly 40 years. This issue is exacerbated within the veteran population because of higher rates of pain, anxiety and other related health issues due to military life. An evaluation of the relationship between opioid and benzodiazepine medication practices at the VA is necessary to improve treatment for mental health and combat-related trauma for veterans. An Approach to Evaluate the Effects of Concomitant Prescribing of Opioids and Benzodiazepines on Veteran Deaths and Suicides investigates the effects of opioid initiation and tapering strategies in the presence of benzodiazepines in veterans. This report explores neurobiology and the principles of addiction and tolerance, in addition to the current use of opioids and benzodiazepines for treating pain and anxiety in both the veteran and general population. It also provides a protocol to evaluate the relationship between opioid and benzodiazepine medication practices. This framework is a critical foundation for further research to improve concomitant opioid and benzodiazepine medication practices for veterans and the general population"--Publisher's description Bibliography Includes bibliographical references Notes Online resource; title from PDF title page (viewed January 31, 2020) Subject Opioid abuse -- Prevention Benzodiazepine abuse -- Prevention Opioids -- Safety measures Benzodiazepines -- Safety measures Veterans -- Medical care -- United States Veterans -- Suicidal behavior -- United States Mortality. Veterans. Opioid-Related Disorders -- complications Benzodiazepines -- adverse effects Off-Label Use Suicide, Completed Mortality Veterans mortality. veterans. Veterans Mortality Benzodiazepines -- Safety measures Veterans -- Medical care United States United States Form Electronic book Author National Academies of Sciences, Engineering, and Medicine (U.S.). Committee on Developing a Protocol to Evaluate the Concomitant Prescribing of Opioids and Benzodiazepine Medications and Veteran Deaths and Suicides, issuing body. ISBN 9780309496001 0309496004 9780309496025 0309496020

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