Title Opiate receptors and antagonists : from bench to clinic / Reginald L. Dean, Edward J. Bilsky, S. Stevens Negus, editors

Published New York, NY : Humana Press, ©2009

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Description 1 online resource (xxiii, 757 pages, 6 unnumbered pages of plates) : illustrations (some color) Series Contemporary neuroscience Contemporary neuroscience. Contents From the contents Opioid Receptors -- Opioid Antagonists: Chemistry And Pharmacology -- Substance Abuse -- Alcohol And Ingestive Behaviors -- Behavioral Disorders -- Medical Indications -- Drug Delivery Approaches Summary The evolution in our understanding of Opioid receptors and their subtypes is intimately linked to the development of new pharmacological treatments for diseases and disorders as diverse as addiction, self-injurious behavior, pain, cancer, inflammation, eating disorders, traumatic injury, pruritis and movement disorders. The contributions contained in Opioid Receptors and Antagonists: From Bench to Clinic represent efforts from leading international scientists and clinicians making use of the latest information emerging from the study of the opioid-receptor system. The authors use a variety of experimental and clinical approaches involving the fields of molecular biology, biochemistry, anatomy, pharmacology, behavioral neuroscience and psychiatry to illustrate rapidly developing experimental and therapeutic areas. Highlights include characterization of opioid receptors, chemistry and pharmacology of opiod antagonists for various receptor subtypes (Mu, Kappa, and Delta), discussion of therapeutic uses of opiod antagonists and exploration of innovative approaches to therapeutic drug delivery. Opioid Receptors and Antagonists: From Bench to Clinic offers a comprehensive view of recent work on opiod antagonist applications and uses in various clinical treatments. Emphasis is placed on disorders of the reward system. This volume serves as reference while also illuminating prospects for future research Bibliography Includes bibliographical references and index Notes Print version record Subject Endorphins -- Receptors. Endorphins -- Antagonists Opioids -- Receptors. Nervous system -- Diseases -- Chemotherapy Narcotic antagonists. Endorphins. Opioid peptides. Endorphin antagonists. Narcotic Antagonists -- therapeutic use Narcotic Antagonists Endorphins Drug Delivery Systems Drug Discovery Opioid Peptides Receptors, Opioid Substance-Related Disorders -- drug therapy MEDICAL -- Pain Medicine. MEDICAL -- Psychiatry -- Psychopharmacology. Opioids -- Receptors. Nervous system -- Diseases -- Chemotherapy. Endorphins. Narcotic Antagonists. Receptors, Opioid. Endorphins -- Receptors. Endorphins -- Antagonists. Sciences de la vie. Biomédecine. Opioid peptides Narcotic antagonists Endorphins Endorphins -- Receptors Nervous system -- Diseases -- Chemotherapy Opioids -- Receptors Form Electronic book Author Dean, Reginald L. Bilsky, Edward J. Negus, S. Stevens. ISBN 9781597451970 1597451975 1588298817 9781588298812 1282038109 9781282038103

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