In this study, AHI1 and NDRG2 gene function in the insulin signalling pathways regulating skeletal muscle homeostasis was investigated. Findings implicate AHI1 in the regulation of insulin-stimulated glucose transport and the development of insulin resistance, whilst associating NDRG2 with the regulation of myoblast proliferation and differentiation; possible via interactions with PICK1 and arfaptin2
Notes
Degree conferred 2009
Submitted to the School of Exercise and Nutrition Sciences of the Faculty of Health, Medicine, Nursing and Behavioural Sciences, Deakin University
Thesis (Ph.D.)--Deakin University, Victoria, 2008
Bibliography
Includes bibliographical references (leaves 194-229)
