An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement
Specialized afferent neurons capable of transducing sensory stimuli into NERVE IMPULSES to be transmitted to the CENTRAL NERVOUS SYSTEM. Sometimes sensory receptors for external stimuli are called exteroceptors; for internal stimuli are called interoceptors and proprioceptors
Neurons -- Effect of drugs on : Neural cell biology / editors, Cheng Wang, Director of Neurotoxicology, National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, AR, USA, William Slikker, Jr., National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), Jefferson, AR, USA
2017
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Neurons, Efferent : Cerebellum : the brain for an implicit self / Masao Ito
2012
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Neurons, Efferent -- physiology : Auditory and vestibular efferents / David K. Ryugo, Richard R. Fay, Arthur N. Popper, editors
Neurons that fire when an animal acts or observes the same action of another thus coding the motor response. They were originally discovered in the premotor and parietal cortex of the monkey and studies have shown that neurons that have a similar mechanism are present in humans. Mirror neurons are theorized to be related to social cognition
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM
Specialized afferent neurons capable of transducing sensory stimuli into NERVE IMPULSES to be transmitted to the CENTRAL NERVOUS SYSTEM. Sometimes sensory receptors for external stimuli are called exteroceptors; for internal stimuli are called interoceptors and proprioceptors
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Neurons -- transplantation : Restorative therapies in Parkinson's disease / Patrik Brundin, C. Warren Olanow, editors
2006
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Neurons -- ultrastructure : The functions, disease-related dysfunctions, and therapeutic targeting of neuronal mitochondria / edited by Valentin K. Gribkoff, Elizabeth A. Jonas, J. Marie Hardwick
2015
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Neurooftalmologi. : Neuro-ophthalmology illustrated / Valérie Biousse, Nancy J. Newman
2009
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Neurooftalmologia. : Controversies in neuro-ophthalmic management : an evidence and case-based appraisal / Amanda D. Henderson, Andrew R. Carey, editors