| Description |
1 online resource (xvi, 523 pages) : illustrations |
| Contents |
Designer mice : scope and sourcebooks -- Of unicorns and chimeras : how to generate a transgenic or knockout mouse for behavioral phenotyping -- General health : give your mouse a physical -- Motor functions : open field, holeboard, rotarod, balance, grip, circadian activity, circling, stereotypy, ataxic gait, seizures -- Sensory abilities : olfaction, vision, hearing, taste, touch, nociception -- Learning and memory : Morris swim task, spatial mazes, cued and contextual conditioning, conditioned taste aversion, conditioned eyeblink, olfactory discrimination, social recognition, passive avoidance, schedule controlled operant tasks, motor learning, attention -- Feeding and drinking : daily consumption, restricted access, choice tests, microstructural analysis -- Reproductive behaviors : sexual and parental behaviors -- Social behaviors : social interaction, nesting, grooming, juvenile play, aggression -- Emotional behaviors : animal models of psychiatric disorders : mouse models of fear, anxiety, depression, schizophrenia -- Reward : self-administration of addictive drugs, conditioned place preference -- Neurodevelopment and neurodegeneration : assaying behaviours in infant, juvenile, and aged mice -- Putting it all together : choice of tests, order of testing, number of mice, equipment, housing and testing environment -- The next generation : conditional and inducible mutations, viral vector gene delivery, RNA silencing, quantitative trait loci analysis, DNA microarrays, chemical mutagenesis, gene therapy, ethical issues |
| Summary |
This new edition of Whats Wrong With My Mouse? continues to provide the most thorough overview of mutant mouse technology and a readable introduction to the field of behavioural neuroscience as applied to behavioural phenotyping of transgenic and knockout mice |
| Bibliography |
Includes bibliographical references (pages 383-501) and index |
| Notes |
English |
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Print version record |
| Subject |
Neurogenetics -- Animal models
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Transgenic mice -- Behavior
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Transgenic mice.
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Animal behavior.
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Diseases -- Animal models.
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Phenotype.
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Neurogenetics.
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Animal models in research.
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Mice, Transgenic
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Behavior, Animal
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Disease Models, Animal
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Genetics, Behavioral -- methods
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Mice, Knockout
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Phenotype
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SOCIAL SCIENCE -- Anthropology -- Physical.
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Transgenic mice
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Phenotype
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Neurogenetics
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Diseases -- Animal models
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Animal models in research
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Animal behavior
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Transgenic mice -- Behavior
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| Form |
Electronic book
|
| LC no. |
2006033565 |
| ISBN |
9780470119051 |
|
0470119055 |
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9780470119044 |
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0470119047 |
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9780471471929 |
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0471471925 |
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9786610822355 |
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6610822352 |
|
