Models and methods for studying neural development -- The anatomy of developing nervous systems -- Neural induction : an early example of how intercellular signalling determines cell fates -- Patterning the neuroectoderm -- Neurogenesis : generating neural cells -- Neuronal migration -- How neurons develop their shapes -- Axon pathfinding : the long and winding road -- Map formation -- Maturation of functional properties -- Life and death in the developing nervous system -- Experience-dependent development
Summary
The development of a brain from its simple beginnings in the embryo to the extraordinarily complex fully-functional adult structure is a truly remarkable process. Understanding how it occurs remains a formidable challenge despite enormous advances over the last century and current intense world-wide scientific research. A greater knowledge of how nervous systems construct themselves will bring huge benefits for human health and future technologies. Unravelling the mechanisms that lead to the development of healthy brains should help scientists tackle currently incurable diseases of the nervous
