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Title Microfluidic and compartmentalized platforms for neurobiological research / edited by Emilia Biffi
Published New York, NY : Humana Press, 2015


Description 1 online resource (xiii, 248 pages) : illustrations (some color)
Series Neuromethods, 0893-2336 ; 103
Neuromethods ; 103. 0893-2336
Contents Fabrication of microfluidic platforms with pneumatically/hydraulically controlled PDMS valves and their use in neurobiological research / Bryson M. Brewer, Donna J. Webb, and Deyu Li -- Reliable reversible bonding method for perfused microfluidic devices / Paola Occhetta, Emilia Biffi, and Marco Rasponi -- Bridging two cultures : minimalistic networks prepared by microfluidic arraying, and open access compartments for electrophysiology / Jonathan West [and others] -- Asymmetric genetic manipulation and patch clamp recording of neurons in a microfluidic chip / Prasanna Sakha [and others] -- Development of a compartmentalized biochip for axonal isolation and neuronal-circuit formation at the single-cell level / Ting Huang [and others] -- Campenot cultures and microfluidics provide complementary platforms for spatial study of dorsal root ganglia neurons / Sara J. Fenstermacher, Maria F. Pazyra-Murphy, and Rosalind A. Segal -- Development of microfluidic devices for the manipulation of neuronal synapses / Anika Jain and Martha U. Gillette -- Use of a 3-compartment microfluidic device to study activity dependent synaptic competition / Ainsley Coquinco and Max Cynader -- Multi-compartment neuron-glia coculture microsystem / Jaewon Park [and others] -- Compartmentalized microfluidic platforms as tool of choice to study the interaction between neurons and osteoblasts / Estrela Neto [and others] -- Novel in vitro primary culture model of the lower motor neuron-neuromuscular junction circuit / Katherine A. Southam [and others] -- Compartmentalized microfluidics for in vitro Alzheimer's disease studies / Yufei Ren, Anja Kunze, and Philippe Renaud -- Selective biochemical manipulation of twin neuronal networks on microelectrode arrays / Giulia Regalia [and others] -- Compartmentalized synapse microarray for high- throughput screening / Amol D. Jadhav [and others]
Summary This volume presents cutting-edge techniques to design, fabricate and use compartmentalized microfluidic devices. Chapters encompass axon guidance and manipulation, compartmentalized devices for synapse manipulation, cell populations interaction either in physiological or pathological condition, and compartmentalized devices for pharmacological research and drug discovery. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Authoritative and practical, Microfluidic and Compartmentalized Platforms for Neurobiological Research provides practical skills needed to fabricate, use microfluidics, and compartmentalized platforms with neuronal cell cultures as well as the strengths of these exciting devices and their precious contribution in the field of Neuroscience
Analysis biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerLink, viewed March 20, 2015)
Subject Microfluidic devices -- Laboratory manuals
Neurobiology -- Laboratory manuals
Nervous system.
Nervous System
Neurobiology -- methods
Microfluidics -- methods.0
Nervous system
Microfluidic devices
Genre/Form Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Biffi, Emilia, editor.
ISBN 9781493925100