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Book Cover
E-book

Title Stem cells and cancer / edited by Sadhan Majumder
Published New York : Springer, ©2009

Copies

Description 1 online resource (xiv, 296 pages) : illustrations (some color)
Contents Cover -- Contents -- Stem Cells and Cancer: An Introduction -- Molecular Regulation of the State of Embryonic Stem Cells -- MicroRNAs in Stem Cells and Cancer Stem Cells -- Cancer Stem Cells and Metastasis: Emerging Themes and Therapeutic Implications -- Stem Cells in Leukemia and Other Hematological Malignancies -- Prostate Cancer Stem Cells -- Breast Cancer Stem Cells -- Stem Cells and Lung Cancer -- Cancer Stem Cells in Colorectal Cancer -- Cancer Stem Cells and Skin Cancer -- Lineage Relationships Connecting Germinal Regions to Brain Tumors -- Index
Summary Cancer is a major cause of human morbidity and mortality worldwide. Despite decades of basic and clinical research, the outcome for many cancer patients is still dismal. Although the existence of "stem-like" cells in cancer was hypothesized more than 150 years ago, recent discoveries have the potential to revolutionize cancer therapy. In particular, we now know that many cancers contain a fraction of self-renewing, drug- and radiation-resistant cells (cancer stem cells or cancer-initiating cells) and it is these cells--and not the major bulk of the tissue--that are the root cause for cancer initiation, relapse and metastasis. In a single volume, Stem Cells and Cancer offers up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies across all major types of cancer. It provides timely, cutting-edge information about cancer stem cells from the perspectives of both the basic and clinical sciences
Analysis celbiologie
cellular biology
neoplasms
biomedische wetenschappen
biomedicine
oncologie
oncology
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Cancer cells.
Carcinogenesis.
Cancer -- Etiology.
Stem cells.
Cancer -- Treatment.
Neoplastic Stem Cells
Stem Cells
Neoplasms
Carcinogenesis
Sciences de la vie.
Biomédecine.
Cancer cells
Cancer -- Etiology
Cancer -- Treatment
Carcinogenesis
Stem cells
Kanker.
Pathogenese.
Stamcellen.
Form Electronic book
Author Majumder, Sadhan
ISBN 9780387896113
0387896112
9780387896106
0387896104
1282287826
9781282287822
9786612287824
6612287829