| Description |
1 online resource |
| Series |
Cancer drug discovery and development |
|
Cancer drug discovery and development.
|
| Contents |
1. Introduction to Ex Vivo Cancer Models -- 2. Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5. Advancing techniques and insights in circulating tumor cell (CTC) research -- 6. The Cancer Secretome -- 7. An overview of the tumor microenvironments and future of cancer therapy |
| Summary |
This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time |
| Bibliography |
Includes bibliographical references |
| Notes |
Online resource; title from PDF title page (EBSCO, viewed December 20, 2016) |
| Subject |
Cancer -- Molecular aspects.
|
|
Tumors -- Molecular aspects
|
|
Biological models.
|
|
Neoplastic Cells, Circulating
|
|
Tumor Microenvironment
|
|
Carcinogenesis
|
|
Models, Biological
|
|
Oncology.
|
|
HEALTH & FITNESS -- Diseases -- General.
|
|
MEDICAL -- Clinical Medicine.
|
|
MEDICAL -- Diseases.
|
|
MEDICAL -- Evidence-Based Medicine.
|
|
MEDICAL -- Internal Medicine.
|
|
Biological models.
|
|
Cancer -- Molecular aspects.
|
| Form |
Electronic book
|
| Author |
Aref, Amir R., editors.
|
|
Barbie, David, editor.
|
| ISBN |
9783319453972 |
|
3319453971 |
|
3319453955 |
|
9783319453958 |
|
