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Author Cancer Stem Cell Workshop (2007? : Berlin-Brandenburg Academy of Sciences and Humanities)

Title Cancer stem cells : novel concepts and prospects for tumor therapy / O.D. Wiestler, B. Haendler, D. Mumberg, editors
Published Berlin ; New York : Springer, 2007


Description 1 online resource (xvi, 263 pages) : illustrations
Series Ernst Schering Foundation symposium proceedings, 0947-6075 ; 2006/5
Ernst Schering Foundation symposium proceedings ; 2006/5. 0947-6075
Contents Niche for normal and cancer stem cells / S.-I. Nishikawa, M. Osawa -- c-Myc and activated Ras during skin tumorigenesis : cooperation at the cancer stem cell level? / A. Trumpp -- Wnt signaling in stem cells and lung cancer / B. He, D.M. Jablons -- Bone morphogenetic proteins regulate tumorigenicity in human glioblastoma stem cells / S.G.M. Piccirillo, A.L. Vescovi -- Strategies to induce nuclear reprogramming / S. Eminli, R. Jaenisch, K. Hochedlinger -- The intestinal stem cell niche studied through conditional transgenesis / A.R. Clarke, V. Meniel -- The migrating cancer stem cells model--a conceptual explanation of malignant tumour progression / A. Jung, T. Brabletz, T. Kirchner -- Bone marrow niche and leukemia / A.D. Ho, W. Wagner -- Breast stem cells and cancer / G. Farnie, R.B. Clarke -- Prostate cancer stem cells : a target for new therapies / N.J. Maitland [and others] -- The hedgehog signaling network, mammary stem cells, and breast cancer : connections and controversies / M.T. Lewis, A.P. Visbal -- Strategies to eliminate cancer stem cells / R.J. Jones -- DNA repair in stem cell maintenance and conversion to cancer stem cells / S.L. Gerson, J. Reese, J. Kenyon -- Tumorigenic epithelial stem cells and their normal counterparts / V.S. Donnenberg [and others]
Summary Cancer stem cells werehave originally been identified in leukemia and later in several solid tumor types. They have very different properties from the bulk of the tumor, as they divide much more slowly and have very efficient drug- resistance mechanisms. Current treatments might largely spare cancer stem cells, thus leading to tumor recurrence and metastasis. The recent identification of growth and differentiation pathways responsible for cancer stem cell proliferation and survival will help in the discovery identification of novel therapeutic targets. Developing selective drugs against cancer
Analysis neoplasms
biomedische wetenschappen
humane genetica
human genetics
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references
Notes English
Print version record
Subject Cancer cells -- Proliferation -- Congresses
Stem cells -- Congresses
Cancer -- Treatment -- Congresses
Neoplastic Stem Cells -- pathology
Signal Transduction -- physiology
Antineoplastic Agents -- pharmacology
Neoplasms -- prevention & control
Neoplastic Stem Cells -- drug effects
Neoplastic Stem Cells
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Antineoplastic Agents -- pharmacology.
Neoplasms -- prevention & control.
Neoplastic Stem Cells -- drug effects.
Signal Transduction -- physiology.
Cancer cells -- Proliferation.
Stem cells.
Cancer -- Treatment.
Neoplastic Stem Cells -- pathology.
Sciences de la vie.
Cancer cells -- Proliferation
Cancer -- Treatment
Stem cells
Genre/Form proceedings (reports)
Conference papers and proceedings
Conference papers and proceedings.
Actes de congr├Ęs.
Form Electronic book
Author Wiestler, O. D. (Otmar D.), 1956-
Haendler, B. (Bernard)
Mumberg, D. (Dominik)
Ernst Schering Research Foundation.
LC no. 2007928117
ISBN 9783540708537