| Description |
1 online resource |
| Contents |
Breast Cancer Statistics / Jiemin Ma and Ahmedin Jemal -- Epidemiology of Breast Cancer in Women / Steven S. Coughlin and Yasmin Cypel -- The Complexities of Racial Disparity in Breast Cancer / Joy Tang, Aamir Ahmad and Fazlul H. Sarkar -- Major Signaling Pathways Involved in Breast Cancer / Saba Wasim Aziz and Moammir Hasan Aziz -- Breast Cancer Heterogeneity in Primary and Metastatic Disease / Jodi M. Saunus, Amy McCart-Reed, Majid Momeny, Margaret Cummings and Sunil R. Lakhani -- Understanding Triple-Negative Breast Cancer / Ayca Gucalp and Tiffany A. Traina -- The Biology of the Deadly Love Connection Between Obesity, Diabetes, and Breast Cancer / Bin Bao, Anthony Oraha, Aamir Ahmad, Shadan Ali and Yiwei Li, et al. -- Progression of Early Breast Cancer to an Invasive Phenotype / Connor D. MacMillan, Ann F. Chambers and Alan B. Tuck -- Pre-Clinical Modeling of Breast Cancer: Which Model to Choose? / Claire Nash and Valerie Speirs -- Modeling Breast Cancer Progression in 4-D / Mansoureh Sameni, Stefanie R. Mullins, Kamiar Moin, Bonnie F. Sloane and Kingsley Osuala -- Bone Metastasis of Breast Cancer / Takae M. Brewer, Richard L. Theriault and Naoto T. Ueno |
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Cellular and Molecular Mechanisms Involved in Breaching of the Blood-Brain Barrier by Circulating Breast Cancer Cells / Hava Karsenty Avraham, Shuxian Jiang, Lili Wang, Yigong Fu and Shalom Avraham -- Resistance to Anthracyclines and Taxanes in Breast Cancer / Derek Edwardson, Simon Chewchuk and Amadeo M. Parissenti -- Understanding Tamoxifen Resistance of Breast Cancer Based on Integrative Bioinformatics Approaches / Y. Dai and L. Huang -- Current Understanding of Drug Resistance Mechanisms and Therapeutic Targets in HER2 Overexpressing Breast Cancers / Aamir Ahmad and Fazlul H. Sarkar -- Platinum and Ruthenium Complexes for the Therapy of Breast Cancer Diseases / Bernhard Biersack and Rainer Schobert -- Development of Notch Pathway Inhibitors for Cancer Therapy / Ingrid Espinoza and Lucio Miele -- Systems Biology Approaches in Breast Cancer Studies / Zhiwei Wang, Shavali Shaik, Hiroyuki Inuzuka and Wenyi Wei -- Epigenetic Factors in Breast Cancer Progression / Samriddhi Shukla and Syed Musthapa Meeran -- Breast Cancer Stem Cells and miRNAs / Saurabh Singh -- Breast Cancer Stem Cells: Responsible for Therapeutic Resistance and Relapse? / Hasan Korkaya and Fayaz Malik -- MicroRNAs in Breast Cancer Research: Progress and Promise / Alia Ahmed, Ashhar S. Ali, Shadan Ali, Aamir Ahmad and Philip A. Philip, et al |
| Summary |
This comprehensive book on breast cancer brings together some of the leading experts in an attempt to better understand breast cancer disease, the factors that make it lethal and current research progress, integrating both basic research with clinical implications. This volume covers the following core issues: i) heterogeneity in breast cancer - statistics, epidemiology, breast cancer subtypes, racial disparity and the associated challenges, ii) available and upcoming model systems in breast cancer research, iii) breast cancer metastasis to bones and brain, iv) drug resistance mechanisms in breast cancer against targeted therapies and v) recent developments in breast cancer research - state of current research directions / technologies / approaches. With its comprehensive coverage of topics related to breast cancer, this volume is expected to have a very wide appeal. It serves as an excellent source of reference for students/beginning researchers just setting foot in the field and interested in getting to know all the aspects of this disease. The book should also appeal to advanced and senior researchers by bringing everyone up-to-date with the most current knowledge on various breast cancer topics of utmost relevance |
| Analysis |
Medicine |
|
Oncology |
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Drug interactions |
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Biomedicine |
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Cancer Research |
|
Drug Resistance |
| Bibliography |
Includes bibliographical references |
| Notes |
English |
| In |
Springer eBooks |
| Subject |
Breast -- Cancer.
|
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Drug resistance in cancer cells.
|
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Drug resistance.
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Breast Neoplasms
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Drug Resistance
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Neoplastic Stem Cells
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Drug Resistance, Neoplasm
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HEALTH & FITNESS -- Diseases -- Cancer.
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MEDICAL -- Oncology.
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Drug resistance
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Breast -- Cancer
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Drug resistance in cancer cells
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| Form |
Electronic book
|
| Author |
Ahmad, Aamir
|
| LC no. |
2012952583 |
| ISBN |
9781461456476 |
|
1461456479 |
|
1461456460 |
|
9781461456469 |
|
1283911884 |
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9781283911887 |
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