Description |
1 online resource |
Contents |
Intro -- Foreword -- Preface -- Introduction -- Contents -- Chapter 1: Porosome: Cells Secretory Nanomachine -- Introduction -- Porosome Discovery -- Porosome Structure and Dynamics -- Porosome: Isolation and Composition -- Porosome: Functional Reconstitution in Lipid Membrane and Live Cells -- Establishment of the t-/v-SNARE Rosette or Ring Complex at the Porosome Base -- Vesicle Volume Regulates Porosome-Mediated Fractional Content Release -- Porosome in Health and Disease -- References -- Chapter 2: Ubiquitin-Proteasome Machinery: Cells Garbage Disposal -- Discovery |
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Proteasome Structure-Function -- Disease and Treatments Targeting the Proteasome -- References -- Chapter 3: Chaperonin: Protein Folding Machinery in Cells -- Discovery -- Structure-Function -- Disease Resulting from Alterations in Chaperonin -- References -- Chapter 4: ATP Synthase: Energy Generating Machinery in Cells -- Discovery and Structure-Function -- Disease Resulting from Altered ATP Synthase -- References -- Chapter 5: Ribosome: Cells Protein Synthetic Machinery -- Discovery -- Structure-Function -- Ribosome in Health and Disease -- References |
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Chapter 6: Nuclear Pore: A Bidirectional Transport Machinery -- Discovery -- Structure-Function -- Defects in Nuclear Transport and Disease -- References -- Chapter 7: Myosin: Cellular Molecular Motor -- Discovery -- Structure-Function -- Altered Motor Protein and Disease -- References -- Chapter 8: Assembly of Cellular Nanomachines -- Membrane-Directed Self-Assembly of t-/v-SNARE Ring Complexes -- Biogenesis of Cellular Membranes -- References -- Index |
Summary |
In this book, the major paradigm-shifting discoveries made in the past century on key cellular nanomachines are described in great detail: their complex yet precise and elegant design and function, as well as the diseases linked to their dysfunction and the therapeutic approaches to overcome them. The major focus of this book is the "porosome" nanomachine, the universal secretory portal in cells. This is an ideal book for students, researchers, and professionals in the fields of nanoscience and nanotechnology |
Bibliography |
Includes bibliographical references and index |
Subject |
Nanoelectromechanical systems.
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Nanotechnology.
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Secretory Vesicles -- physiology
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Secretory Vesicles -- ultrastructure
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Cellular Structures -- physiology
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Cellular Structures -- ultrastructure
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Nanostructures -- ultrastructure
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Nanotechnology
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Nanoelectromechanical systems
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Nanociència.
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Nanotecnologia.
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Genre/Form |
Llibres electrònics.
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Form |
Electronic book
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ISBN |
9783030444969 |
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3030444961 |
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9783030444976 |
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303044497X |
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9783030444983 |
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3030444988 |
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