| Description |
1 online resource (xxxix, 485 pages) : illustrations |
| Series |
Mechanosensitivity in cells and tissues ; v. 3 |
|
Mechanosensitivity in cells and tissues (Series) ; v. 3.
|
| Contents |
Molecular Mechanisms of Mechanotransduction in Cardiac Cells -- Titin and Titin-Associated Proteins in Myocardial Stress-Sensing and Mechanical Dysfunction -- Mechanical Stretch-Induced Reorganization of the Cytoskeleton and the Small GTPase Rac-1 in Cardiac Fibroblasts -- Molecular Signaling Mechanisms of Myocardial Stretch: Implications for Heart Disease -- Mechanical Stress Induces Cardiomyocyte Hypertrophy Through Agonist-Independent Activation of Angiotensin II Type 1 Receptor -- Mechanically Induced Potentials and Currents of the Cardiac Cells in Healthy and Diseased Myocardium -- Mechanostransduction in Cardiac and Stem-Cell Derived Cardiac Cells -- Stretch-Activated Channels in the Heart: Contribution to Cardiac Performance -- Effects of Applied Stretch on Native and Recombinant Cardiac Na+ Currents -- Mechanosensitive Alterations of Action Potentials and Membrane Currents in Healthy and Diseased Cardiomyocytes: Cardiac Tissue and Isolated Cell -- The Role of Mechanosensitive Fibroblasts in the Heart: Evidence from Acutely Isolated Single Cells, Cultured Cells and from Intracellular Microelectrode Recordings on Multicellular Preparations from Healthy and Diseased Cardiac Tissue -- Scanning Ion Conductance Microscopy for Imaging and Mechanosensitive Activation of Selected Areas of Live Cells -- Mechano-Electric Feedback in the Whole Heart and a Computer Simulation Study -- The Contribution of MEF to Electrical Heterogeneity and Arrhythmogenesis -- Mechanical Modulation of a Reentrant Arrhythmia: The Atrial Flutter Case -- Early Hypertrophic Signals After Myocardial Stretch. Role of Reactive Oxygen Species and the Sodium/Hydrogen Exchanger -- Stretch-Induced Inotropy in Atrial and Ventricular Myocardium -- Effects of Wall Stress on the Dynamics of Ventricular Fibrillation: A Computer Simulation Study of Mechanoelectric Feedback -- Electromechanical Modelling of Cardiac Tissue -- Arteries as a Source of Myogenic Contractile Activity: Ionic Mechanisms -- Specific Mechanotransduction Signaling Involved in Myogenic Responses of the Cerebral Arteries |
| Summary |
Presents findings in field of research of mechanosensitivity of the heart. This book focuses on molecular mechanisms of mechanotransduction in cardiac cells. It contains a description of several stretch-induced signaling cascades with multiple levels of crosstalk between different pathways |
| Analysis |
fysiologie |
|
physiology |
|
celbiologie |
|
cellular biology |
|
biochemie |
|
biochemistry |
|
biomedische wetenschappen |
|
biomedicine |
|
cardiologie |
|
cardiology |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Heart.
|
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Mechanoreceptors.
|
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Heart -- physiology
|
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Mechanotransduction, Cellular
|
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Myocardium -- physiology
|
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Heart
|
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Mechanoreceptors
|
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MEDICAL -- Physiology.
|
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SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
|
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Biomédecine.
|
|
Sciences de la vie.
|
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Heart
|
|
Mechanoreceptors
|
| Form |
Electronic book
|
| Author |
Fedorov, Vadim V
|
|
Kamkin, A. G. (Andreĭ Glebovich)
|
|
Kiseleva, I. (Irina)
|
| ISBN |
9789048128501 |
|
9048128501 |
|
