Title Inflammatory cardiomyopathy (DCMi) : pathogenesis and therapy / Heinz-Peter Schultheiss, Michel Noutsias, editors

Published Basel : Birkhäuser, ©2010

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Description 1 online resource (xii, 294 pages) : illustrations Series Progress in inflammation research PIR (Series) Contents Cover -- Table of Contents -- List of Contributors -- Preface -- Myocarditis and Inflammatory Cardiomyopathy 8211; Clinical Management, Epidemiology and Prognosis -- Pathogenesis, Diagnosis and Treatment of Pericarditis -- Classification and Etiology of Pericardial Disease -- Pericardial Syndromes -- Acute Pericarditis -- Chronic Pericarditis -- Recurrent (Relapsing) Pericarditis -- Pericardial Effusion -- Cardiac Tamponade -- Constrictive Pericarditis -- Specific Forms of Pericarditis -- Viral Pericarditis -- Bacterial (Purulent) Pericarditis -- Tuberculous Pericarditis -- Pericarditis in Renal Failure -- Autoreactive Pericarditis -- Post-Cardiac Injury Syndrome -- Traumatic Pericardial Effusion -- Neoplastic Pericarditis -- References -- Epidemiology and Prognosis of Myocarditis and Dilated Cardiomyopathy: Predictive Value of Clinical Parameters and Biopsy Findings -- Pathological Features -- Clinical Presentations -- Natural History -- Predictors of Outcome -- Indications for Endomyocardial Biopsy -- Conclusions -- References -- Animal Models of Myocarditis 8211; Autoimmunity and Viral Infection; Therapeutic Interventions -- Autoimmune Murine Myocarditis and Immunomodulatory Interventions -- The Murine Autoimmune Myocarditis Models -- Targeting the Recruitment of Inflammatory Cells in Murine Autoimmune Myocarditis -- Targeting T Cells in Autoimmune Murine Myocarditis -- Modulating Different T Helper Cell Subsets in Murine Autoimmune Myocarditis -- Pharmacological Interventions in Murine Autoimmune Myocarditis -- Conclusions -- References -- Coxsackievirus-Induced Murine Myocarditis and Immunomodulatory Interventions -- Introduction -- Cvb-Induced Myocarditis in Inbred Murine Strains 8211; A Clue to the Genetics of Disease Susceptibility -- Pathogenesis and Distinct Phases of Cvb-Induced Myocarditis -- Specific Therapeutic Strategies in Cvb-Induced Murine Myocarditis -- Interference With Viral Entry Mechanisms and Antiviral Immunomodulation -- Immunosuppression -- Immunomodulation of T Cell Response -- Immunomodulation of Humoral Response -- Immunomodulation With Cytokines -- Immunomodulation of the Innate Immune System -- References -- Myocardial Proteases and Matrix Remodeling In Acute Myocarditis and Inflammatory Cardiomyopathy -- Introduction -- Inflammation and Cytokines in Amc and Dcm -- Myocardial Ecm: Collagen Network, Regulation of Mmps and Timps, and Effects of Cytokines -- Heart Failure, Cytokines and Ecm Remodeling -- Remodeling of the Ecm in Amc and Dcmi -- Conclusions -- References -- Alterations of the Immune System in Human Viral and Inflammatory Cardiomyopathy -- Molecular Genetics of Cardiomyopathies and Myocarditis -- Introduction -- Normal Cardiac Structure -- Dilated Cardiomyopathy -- Clinical Genetics of Dcm -- Molecular Genetics of Dcm -- X-Linked Cardiomyopathies -- Autosomal Dominant Dcm -- Lamin A/C -- Muscle Is Muscle: Cardiomyopathy and Skeletal Myopathy Genes Overlap -- Hypertrophic Cardiomyopathy -- Clinical Aspects of Hcm -- Genetics of Familial Hcm -- Gene Identification in Fhc -- Thick Fi Summary Cardiomyopathy is one of the most frequent causes of heart failure. It is often associated with inadequate heart pumping or other heart function abnormalities. There are many different causes of the disease, therefore many different kinds of cardiomyopathies exist. This volume, written by a leading expert, focuses on inflammatory CM, belonging to the Dilated Cardiomyopathies (DCMi). It covers epidemiology/prognosis, pathology, immunology, diagnosis and treatment strategies Bibliography Includes bibliographical references and index Notes English Print version record In Springer eBooks Subject Myocarditis. Toxicology. Myocarditis -- immunology Cardiomyopathies -- therapy Myocarditis Toxicology toxicology. HEALTH & FITNESS -- Diseases -- Heart. MEDICAL -- Cardiology. Médecine. Myocarditis Form Electronic book Author Schultheiss, H.-P. (Heinz-Peter), 1948- Noutsias, Michel. ISBN 9783764383527 3764383526 9783764383510 3764383518 1283076683 9781283076685 9786613076687 6613076686

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