Diagnosis and control of Johne's disease / Committee on Diagnosis and Control of Johne's Disease, Board on Agriculture and Natural Resources, Division on Earth and Life Sciences, National Research Council of the National Academies
DIAGNOSIS AND CONTROL OF JOHNE'S DISEASE -- Copyright -- Acknowledgments -- Preface -- Contents -- Executive Summary -- THE TASK -- CONCLUSIONS -- DISEASE CONTROL -- EDUCATION AND TRAINING -- RESEARCH -- Epidemiology of Map Infection and JD -- Diagnostics and Immunology -- Map Genome Studies -- Vaccine Development -- Human and Animal Health Issues -- 1 Introduction -- THE COMMITTEE'S TASK -- 2 Johne's Disease in Domesticated and Wild Animals -- SPECTRUM OF DISEASE IN DOMESTICATED ANIMALS -- Cattle -- Stage I: Silent Infection
Stage II: Subclinical DiseaseStage III: Clinical Disease -- Stage IV: Advanced Clinical Disease -- Sheep and Goats -- SPECTRUM OF DISEASE IN OTHER ANIMALS -- PATHOLOGY -- Cattle -- Lesions of Subclinical Infection -- Lesions of Clinical Infection -- Sheep -- Goats -- Exotic Ruminants -- Non-ruminant Species -- Primates -- Rabbits -- Other Species -- EPIDEMIOLOGY -- Global Prevalence in Domesticated Animals -- Prevalence in Wildlife and Zoo Animals -- MODES OF TRANSMISSION -- Fecal-Oral Transmission -- Congenital Transmission
Lactation TransmissionCross-Species Transmission -- Sanitation -- Environmental Factors -- Water -- Soil Characteristics -- Pasteurization -- PATHOGENESIS IN CATTLE -- Age-Related Susceptibility -- Genetic Susceptibility -- Immune Response -- Sequencing of the Map Genome -- 3 Diagnostics -- TESTING OF DOMESTICATED ANIMALS -- Bacteriologic Culture -- Decontamination of Specimens -- Concentration of Map from Specimens -- Conventional Culture for Map -- Automated Culture -- Radiometric Systems -- Nonradiometric Systems -- Pooled Fecal Culture
Sensitivity of Fecal CultureImmunologic Tests -- Detecting the Cell-Mediated Response -- Skin Testing -- Lymphocyte Blastogenesis and Transformation -- Gamma Interferon -- Serologic Tests to Detect the Humoral Response -- Complement Fixation Test -- Agar Gel Immunodiffusion -- Enzyme-Linked Immunosorbent Assay -- Test Result Measures -- Fixed-Decision Thresholds or Cutoffs -- Information Cost and Degree of Result Categorization -- Likelihood Ratios and ROC Curves -- MOLECULAR METHODS -- IS900 -- Molecular Strain Typing -- EPIDEMIOLOGIC TOOLS
Test Protocol StandardizationLaboratory Proficiency Evaluation -- 4 Control Principles and Programs -- CONTROL PRINCIPLES -- Environmental Factors in Infection Control Practices -- Producer Awareness and Adoption of Biosecurity Practices and Control Measures -- Control Programs with a Single-Agent Focus -- Vaccination -- Herd-Level Control -- Dairy Herds -- Beef Herds -- Sheep Flocks -- Goat Herds -- Zoos and Game Farms -- CURRENT CONTROL PROGRAMS -- National Programs -- NJWG and Control Plans -- NJWG 1998 Program -- USDA 2002 Program
Analysis
Andre fag (naturvidenskab og teknik) Andre fag
Bibliography
Includes bibliographical references (pages 133-174)